Results 11 to 20 of about 16,632 (221)

Genetics of Neurogenic Orthostatic Hypotension in Parkinson’s Disease, Results from a Cross-Sectional In Silico Study [PDF]

Brain Sciences, 2023
The genetic basis of Neurogenic Orthostatic Hypotension (NOH) in Parkinson’s disease (PD) has been inadequately explored. In a cross-sectional study, we examined the association between NOH and PD-related single-nucleotide polymorphisms (SNPs) and mapped
Guenson Chevalier, Lucas Udovin, Matilde Otero-Losada, Sofia Bordet, Francisco Capani, Sheng Luo, Christopher G. Goetz, Santiago Perez-Lloret   +7 more
doaj   +3 more sources

Neurogenic orthostatic hypotension after treatment with sorafenib. [PDF]

BMJ Case Rep, 2022
A man in his 70s with a history of fatigue, abdominal pain, and a palpable abdominal mass was found to have a peritoneal desmoid tumour. One year after diagnosis, he was prescribed sorafenib to limit tumour growth. Two months later, he developed dyspnoea
Wegner Wippel C, Deshpande H, Patwa H, Peixoto AJ.   +3 more
europepmc   +4 more sources

Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer [PDF]

Neurology and Therapy, 2019
Abstract Parkinson disease (PD) is associated with a variety of motor and non-motor clinical manifestations, including cardiovascular autonomic dysfunction. Neurogenic orthostatic hypotension (nOH) is a potentially serious manifestation of cardiovascular
Jeremy K. Cutsforth-Gregory, Phillip A. Low   +1 more
doaj   +5 more sources

Psychometric validation of a patient-reported single-item assessment of ‘Good Day Bad Day’ in a neurogenic orthostatic hypotension population treated with droxidopa [PDF]

Journal of Market Access & Health Policy, 2022
Background Symptoms of neurogenic orthostatic hypotension (nOH), including lightheadedness/dizziness, presyncope, syncope, and falls, can lead to impaired functional ability and reduced quality of life.
Clément François, Nicola Germain, Renata Majewska, Vanessa Taieb, L. Arthur Hewitt, Steven Kymes   +5 more
doaj   +3 more sources

Neurogenic Orthostatic Hypotension in Parkinson Disease-A Narrative Review of Diagnosis and Management. [PDF]

J Clin Med
Background: Neurogenic orthostatic hypotension (NOH) is a significant non-motor manifestation of Parkinson’s disease (PD), that substantially affects patient disability and has a powerful impact on the quality of life of PD patients, while also ...
Grosu C, Noea O, Maștaleru A, Ignat EB, Leon MM.   +4 more
europepmc   +2 more sources

Ampreloxetine Versus Droxidopa in Neurogenic Orthostatic Hypotension: A Comparative Review. [PDF]

Cureus, 2023
Neurogenic orthostatic hypotension (nOH) is a disabling problem of autonomic dysfunction in patients with Parkinson’s disease, which is associated with poor quality of life and higher mortality rates.
Hoxhaj P, Shah S, Muyolema Arce VE, Khan W, Sadeghzadegan A, Singh S, Collado GF, Goyal A, Khawaja I, Botlaguduru D, Razzaq W, Abdin ZU, Gupta I.   +12 more
europepmc   +2 more sources

Neurogenic orthostatic hypotension in Parkinson's disease: is there a role for locus coeruleus magnetic resonance imaging? [PDF]

J Neural Transm (Vienna), 2023
Locus coeruleus (LC) is the main noradrenergic nucleus of the brain, and degenerates early in Parkinson’s disease (PD). The objective of this study is to test whether degeneration of the LC is associated with orthostatic hypotension (OH) in PD.
Palermo G, Galgani A, Bellini G, Lombardo F, Martini N, Morganti R, Paoli D, De Cori S, Frijia F, Siciliano G, Ceravolo R, Giorgi FS.   +11 more
europepmc   +2 more sources

Effects of Daily Lifestyle Habits on Non-Neurogenic Orthostatic Hypotension in Older Adults in South Korea: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Background: Orthostatic hypotension (OH) is a chronic, debilitating condition common in older adults. This study examined the effects of daily lifestyle habits on non-neurogenic OH in older adults in South Korea.
Kim N, Oh HK.
europepmc   +2 more sources

Neurogenic Orthostatic Hypotension: a Common Complication of Successful Pancreas Transplantation [PDF]

Transplantation Direct, 2021
Background. Orthostatic hypotension (OH) is a poorly understood complication of simultaneous pancreas–kidney (SPK) transplantation. We sought to determine the incidence, timing, and relationship of OH to rapid glycemic control in the early posttransplant
Samantha A. Kuten, PharmD, Edward A. Graviss, PhD, Duc T. Nguyen, PhD, A. Osama Gaber, MD, Archana R. Sadhu, MD, Ericka P. Simpson, MD, Stephanie G. Yi, MD, Hemangshu Podder, MD, PhD, Anna Kagan, MD, PhD, Richard J. Knight, MD   +9 more
doaj   +2 more sources

Unraveling the stride: exploring the influence of neurogenic orthostatic hypotension on gait and balance in Parkinson's disease. [PDF]

Clin Auton Res
Neurogenic orthostatic hypotension (nOH) and gait impairment are frequent sources of disability in Parkinson’s disease (PD). However, the impact of nOH on balance and gait features remains unclear. This cross-sectional study aimed to assess the influence
Imbalzano G, Ledda C, Tangari MM, Artusi CA, Montanaro E, Rizzone MG, Zibetti M, Lopiano L, Romagnolo A.   +8 more
europepmc   +2 more sources