Results 31 to 40 of about 494,114 (145)

Humoral and Mucosal Antibody Response to RSV Structural Proteins in RSV-Infected Adult Hematopoietic Cell Transplant (HCT) Recipients

Viruses, 2021
Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection in infants, the elderly, and immunocompromised patients. RSV antibodies play a role in preventing reinfection and in clearance of RSV, but data regarding the ...
Xunyan Ye, Obinna P. Iwuchukwu, Vasanthi Avadhanula, Letisha O. Aideyan, Trevor J. McBride, David M. Henke, Kirtida D. Patel, Felipe-Andres Piedra, Laura S. Angelo, Dimpy P. Shah, Roy F. Chemaly, Pedro A. Piedra   +11 more
doaj   +1 more source

Influenza Virus-cell Fusion Inhibition Assay

Bio-Protocol, 2013
During viral infection to host cells, several viruses undergo the process of endocytosis and pH-dependent fusion. By fusion of viral membrane with host cellular membrane, the viral core invades to host cytoplasm.
Mayo Yasugi, Kazuyoshi Ikuta
doaj   +1 more source

Prevalence of chikungunya virus infection in Sabah, Malaysia during 2017–2020

Tropical Medicine and Health
Background Chikungunya virus (CHIKV) is a mosquito-borne alphavirus and an emerging global health threat. Most research on CHIKV in Malaysia has primarily focused on Peninsular Malaysia, with limited data on its distribution in the endemic regions of ...
Mya Myat Ngwe Tun, Jecelyn Leaslie John, Thanh Vu Nguyen, Maurine Mumo Mutua, Abdul Marsudi Manah, Yuki Takamatsu, Takeshi Urano, Kouichi Morita, Kamruddin Ahmed   +8 more
doaj   +1 more source

Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier

mBio, 2020
HIV-1 can cross the blood-brain barrier (BBB) to penetrate the brain and infect target cells, causing neurocognitive disorders as a result of neuroinflammation and brain damage.
Valérie Lorin, Anne Danckaert, Françoise Porrot, Olivier Schwartz, Philippe V. Afonso, Hugo Mouquet   +5 more
doaj   +1 more source

A high-throughput screening assay to identify inhibitory antibodies targeting alphavirus release

Virology Journal, 2022
Background Several studies have demonstrated neutralizing antibodies to be highly effective against alphavirus infection in animal models, both prophylactically and remedially.
Anushka Ramjag, Sergej Cutrone, Kai Lu, Christine Crasto, Jing Jin, Sonia Bakkour, Christine V. F. Carrington, Graham Simmons   +7 more
doaj   +1 more source

Post-Immune Antibodies in HIV-1 Infection in the Context of Vaccine Development: A Variety of Biological Functions and Catalytic Activities

Vaccines, 2022
Unlike many other viruses, HIV-1 is highly variable. The structure of the viral envelope changes as the infection progresses and is one of the biggest obstacles in developing an HIV-1 vaccine.
Anna Timofeeva, Sergey Sedykh, Georgy Nevinsky   +2 more
doaj   +1 more source

SIGNIFICANCE OF BIVALENCE OF ANTIBODY IN VIRAL NEUTRALIZATION [PDF]

The Journal of Experimental Medicine, 1971
The role of bivalence of antibody in its capacity to neutralize virus was studied with rabbit antibodies to the bacteriophage, ϕX174. Univalent Fab or Fab' fragments of IgG isolated from antiviral antisera obtained early in the immunization schedule had virtually no activity compared to that of the intact IgG.
Robert W. Rosenstein, Jonathan W. Uhr, Alfred Nisonoff   +2 more
openaire   +3 more sources

DETECTION OF THE BOVINE VIRAL DIARRHEA ANTIBODIES [PDF]

Biotechnologia Acta, 2013
Bovine viral diarrhea is a widespread infection of cattle that has a wide range of clinical symptoms in domestic and wild ruminants. It is a major problem in cattle and causes significant economic losses in the cattle industry.
I. V. Goraichuk, V. I. Bolotin, A. P. Gerilovych, O. S. Solodyankin, R. O. Kucheryavenko, V. V. Kucheryavenko   +5 more
doaj   +1 more source

MONOCLONAL ANTIBODIES AND RECOMBINANT PROTEINS OF FILOVIRUSES: IMMUNOCHEMICAL PROPERTIES AND EVALUATION OF THEIR EFFICIENCY FOR IMMUNE DIAGNOSTICS OF MARBURG AND EBOLA VIRUSES

Медицинская иммунология, 2014
A panel of monoclonal antibodies (MAbs) against VP35, VP40 and NP viral proteins of Marburg and Ebola viruses, as well as recombinant VP35, VP40 and NP proteins were generated and tested for their capacity to specific immune reactions.
E. I. Kazachinskaia, A. V. Ivanova, A. V. Sorokin, E. L. Subbotina, A. V. Kachko, I. A. Razumov, V. B. Loktev   +6 more
doaj   +1 more source

Application of I131 to Determination of Viral Antibodies

Experimental Biology and Medicine, 1955
SummaryExperiments are described in which preparations of yellow fever virus, Bwamba fever virus and influenza virus were allowed to react with corresponding antisera labeled with radioactive iodine (I131). No significant differences were observed in the activity of the sediments obtained with the first 2 virus systems from those of appropriate ...
Delphine H. Clarke, Francis L. Black
openaire   +3 more sources