Results 31 to 40 of about 468,918 (185)
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
On Ordered Harmonic Bounded Variation [PDF]
An example is given of a continuous real function that is of ordered harmonic bounded variation but not of harmonic bounded variation.
openaire +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Optimal Integration for Functions of Bounded Variation [PDF]
The unique optimal information and the unique optimal linear algorithm are obtained for the integration of functions of bounded variation.
Traub, Joseph F., Lee, David
openaire +4 more sources
Efficient finite dimensional approximations for the bilinear Schrodinger equation with bounded variation controls [PDF]
This the text of a proceeding accepted for the 21st International Symposium on Mathematical Theory of Networks and Systems (MTNS 2014). We present some results of an ongoing research on the controllability problem of an abstract bilinear Schrodinger ...
Boussaid, Nabile+2 more
core +2 more sources
Nonlinear diffusion in transparent media: the resolvent equation
We consider the partial differential equation $$ u-f={\rm div}\left(u^m\frac{\nabla u}{|\nabla u|}\right) $$ with $f$ nonnegative and bounded and $m\in\mathbb{R}$.
Giacomelli, Lorenzo+2 more
core +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Non-Autonomous Maximal Regularity for Forms of Bounded Variation [PDF]
We consider a non-autonomous evolutionary problem \[ u' (t)+\mathcal A (t)u(t)=f(t), \quad u(0)=u_0, \] where $V, H$ are Hilbert spaces such that $V$ is continuously and densely embedded in $H$ and the operator $\mathcal A (t)\colon V\to V^\prime$ is ...
Dier, Dominik
core
In this work, we introduce a new method to prove the existence and uniqueness of a variational solution to the stochastic nonlinear diffusion equation $dX(t)={\rm div} [\frac{\nabla X(t)}{|\nabla X(t)|}]dt+X(t)dW(t) in (0,\infty)\times\mathcal{O},$ where
Barbu, Viorel, Röckner, Michael
core +1 more source