Results 31 to 40 of about 60,656 (287)

Cardiomyopathies in China: A 2018–2019 state-of-the-art review

Chronic Diseases and Translational Medicine, 2020
Cardiomyopathies are diseases of the cardiac muscle and are often characterized by ventricular dilation, hypertrophy, and cardiac arrhythmia. Patients with cardiomyopathies often experience sudden death and cardiac failure and require cardiac ...
Tian-Rui Hua, Shu-Yang Zhang
doaj   +1 more source

Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]

, 2014
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core   +2 more sources

Transcriptome data analysis of primary cardiomyopathies reveals perturbations in arachidonic acid metabolism

Frontiers in Cardiovascular Medicine, 2023
IntroductionCardiomyopathies are complex heart diseases with significant prevalence around the world. Among these, primary forms are the major contributors to heart failure and sudden cardiac death.
Pankaj Kumar Chauhan, Ramanathan Sowdhamini, Ramanathan Sowdhamini, Ramanathan Sowdhamini   +3 more
doaj   +1 more source

Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy. [PDF]

, 2015
Background: Hypertrophic cardiomyopathy (HCM) is a common genetic heart disorder characterized by unexplained left ventricle hypertrophy associated with non-dilated ventricular chambers.
BOTTILLO, IRENE, CAPUTO, VIVIANA, Castori, M, D'ANGELANTONIO, DANIELA, De Bernardo, C, Giannarelli, D, GRAMMATICO, Paola, LIPARI, MARTINA, Majore, S, PAIARDINI, ALESSANDRO, PIZZUTI, Antonio, Re, F, Zachara, E   +12 more
core   +1 more source

Targeting lipid metabolism as a new therapeutic strategy for inherited cardiomyopathies

Frontiers in Cardiovascular Medicine, 2023
Inherited cardiomyopathies caused by pathological genetic variants include multiple subtypes of heart disease. Advances in next-generation sequencing (NGS) techniques have allowed for the identification of numerous genetic variants as pathological ...
Karen R. Gaar-Humphreys, Karen R. Gaar-Humphreys, Alyssa van den Brink, Alyssa van den Brink, Mark Wekking, Mark Wekking, Folkert W. Asselbergs, Folkert W. Asselbergs, Frank G. van Steenbeek, Frank G. van Steenbeek, Frank G. van Steenbeek, Magdalena Harakalova, Magdalena Harakalova, Magdalena Harakalova, Jiayi Pei, Jiayi Pei, Jiayi Pei   +16 more
doaj   +1 more source

A rare case report of hypertrophic cardiomyopathy induced by catecholamine-producing tumor [PDF]

, 2018
RATIONALE: Catecholamine-producing tumors are rare, occurring in less than 0.2% of patients with hypertension, but can have relevant cardiovascular morbidity and mortality. PATIENT CONCERNS: A 37-year-old woman presented with a history of dyspnea, chest
Bisogni, Valeria, Bonvicini, Maria, Ciardi, Antonio, Concistré, Antonio, De Toma, Giorgio, Frustaci, Andrea, Iannucci, Gino, Letizia, Claudio, Mezzadri, Martina, Oliviero, Gaia, Olmati, Federica, Petramala, Luigi, Saracino, Vincenza   +12 more
core   +1 more source

A very rare cause of pre‐capillary pulmonary hypertension: The PAMI syndrome

Pulmonary Circulation, 2023
We report the first known case of PAMI syndrome associated with pulmonary arterial hypertension (PAH) with a positive response to cyclophosphamide and pulmonary vasodilators. The patient's history began at 7 months with severe pancytopenia and fever.
Manuela Iseppi, Giulio Savonitto, Alberto Tommasini, Alessia Pin, Gianfranco Sinagra, Davide Stolfo   +5 more
doaj   +1 more source

Sudden Death and Left Ventricular Involvement in Arrhythmogenic Cardiomyopathy [PDF]

, 2019
BACKGROUND: Arrhythmogenic cardiomyopathy (ACM) is an inherited heart muscle disorder characterized by myocardial fibrofatty replacement and an increased risk of sudden cardiac death (SCD).
Asimaki, A, Basu, J, Behr, ER, Cook, SA, Ensam, B, Finocchiaro, G, Gray, B, Malhotra, A, Miles, C, Papadakis, M, Papatheodorou, E, Parry-Williams, G, Paterson, C, Robertus, JL, Sharma, S, Sheppard, MN, Ster, IC, Tome, M, Ware, JS, Westaby, J, Witney, A   +20 more
core   +1 more source

Infiltrative Cardiomyopathies

Clinical Medicine Insights: Cardiology, 2015
Infiltrative cardiomyopathies can result from a wide spectrum of both inherited and acquired conditions with varying systemic manifestations. They portend an adverse prognosis, with only a few exceptions (ie, glycogen storage disease), where early ...
David Bejar, Paolo C. Colombo, Farhana Latif, Melana Yuzefpolskaya   +3 more
doaj   +2 more sources