Results 31 to 40 of about 58,328 (279)

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou, Hana Kubova, Stéphane Auvin, Massimo Mantegazza, Melissa Barker‐Haliski, Aristea S. Galanopoulou, Christopher A. Reid, Bridgette D. Semple   +7 more
wiley   +1 more source

Isolated transient vertigo: posterior circulation ischemia or benign origin?

BMC Neurology, 2017
Background Isolated transient vertigo can be the only symptom of posterior circulation ischemia. Thus, it is important to differentiate isolated vertigo of a cerebrovascular origin from that of more benign origins, as patients with cerebral ischemia have
Tobias F. Blasberg, Lea Wolf, Christian Henke, Matthias W. Lorenz   +3 more
doaj   +1 more source

Closed cranial window rodent model for investigating hemodynamic response to elevated intracranial pressure

Animal Models and Experimental Medicine, 2021
Background Elevated intracranial pressure (ICP) occurs in several physiological and pathological conditions, yet long‐term sequellae are not common, which implies that blood flow is preserved above ischemic thresholds.
Matt T. Oberdier, James F. Antaki, Alexander Kharlamov, Stephen C. Jones   +3 more
doaj   +1 more source

Preliminary study on internal carotid artery perfusion imaging and clinical application based on digital subtraction angiography

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
Background DSA is an irreplaceable diagnostic method for cerebral vascular disease. It is sensitive to intracranial macrovascular disease, but not to distal blood perfusion. In order to quantitatively assess the perfusion area of the feeding artery, this
HU Zhen , JIN Wei, YIN Dou, DENG Yu⁃lei , LIU Jun , LI Bin⁃yin   +5 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

The translational potential of experimental pharmacology for cerebrovascular disorders

Анналы клинической и экспериментальной неврологии, 2019
The efficacy of reperfusion therapy to restore cerebral blood supply in patients with ischaemic cerebrovascular disorders is well recognized. Medications with proven cerebrovascular activity, such as oxymethylethylpyridine succinate (Mexidol), nicotinoyl-
Ruben S. Mirzoian, Tamara S. Gan’shina, Galina A. Kim, Elena V. Kurza, Denis V. Maslennikov, Il'ya N. Kurdyumov, Antonina I. Turilova, Aleksander A. Gorbunov   +7 more
doaj   +1 more source

Ablation of Vitamin D Signaling Compromises Cerebrovascular Adaptation to Carotid Artery Occlusion in Mice

Cells, 2020
Vitamin D insufficiency has been associated with increased incidence and severity of cerebrovascular disorders. We analyzed the impact of impaired vitamin D signaling on the anatomical and functional aspects of cerebrovascular adaptation to unilateral ...
Éva Pál, László Hricisák, Ágnes Lékai, Dorina Nagy, Ágnes Fülöp, Reinhold G. Erben, Szabolcs Várbíró, Péter Sándor, Zoltán Benyó   +8 more
doaj   +1 more source

The clinical effect analysis of internal maxillary artery⁃radial artery⁃cerebral artery bypass for the treatment of cerebral vascular disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
Objective To investigate the clinical effect of cerebral vascular disease treated by transplantations of the short⁃segment radial artery (RA) using the internal maxillary artery (IMA) as the feeding artery.
TONG Zhi⁃yong , LIU Yuan, WANG Gang, SUN Huai⁃yu, YU Guan⁃dong, ZHANG Jin⁃song , CHU Jin⁃gang   +6 more
doaj   +1 more source

Study on the efficacy of compound porcine cerebroside and ganglioside injection in patients with ischemic stroke: A randomized, single‐center, open‐label, prospective study

Ibrain, EarlyView., 2023
Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat ischemic stroke. However, there was no clinical evidence of low‐dose CPCGI. We conducted a clinical study to analyze whether the clinical results of low‐dose and standard‐dose CPCGI in patients with ischemic stroke were different.
Ya Chen, Xia Zhang, Hai‐Qing Zhang, Zhong Luo, Xue‐Jiao Zhou, Tao Liang, Fei Yang, Jun Zhang, Zu‐Cai Xu   +8 more
wiley   +1 more source

Quantitative Analysis of Brain CT Perfusion in Healthy Beagle Dogs: A Pilot Study

Veterinary Sciences, 2023
Brain computed tomography (CT) perfusion is a technique that allows for the fast evaluation of cerebral hemodynamics. However, quantitative studies of brain CT perfusion in veterinary medicine are lacking. The purpose of this study was to investigate the
Soyon An, Gunha Hwang, Seul Ah Noh, Hee Chun Lee, Tae Sung Hwang   +4 more
doaj   +1 more source