Results 31 to 40 of about 10,656,156 (361)
The recent discovery demonstrating that the leakage of cathepsin B from mitotic lysosomes assists mitotic chromosome segregation indicates that lysosomal membrane integrity can be spatiotemporally regulated.
Jonathan Stahl-Meyer +4 more
doaj +1 more source
Ferroptosis: friend or foe in cancer immunotherapy?
Ferroptosis has gained interest due to it immunogenicity and the higher sensitivity of cancer cells to it. However, it was recently shown that ferroptosis in tumor-associated neutrophils leads to immunosuppression and negatively impacts therapy. Here, we
Robin Demuynck +3 more
doaj +1 more source
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown ...
Yael Gavrieli +2 more
semanticscholar +1 more source
Transplantation of the heart after circulatory death of the donor: time for a change in law? [PDF]
Procurement of organs has always been conducted according to the dead donor rule, that is, after death of the donor — but this practice is being challenged. Introduction Australia has an increasing shortfall in transplantable hearts.
James Tibballs, Neera Bhatia
core +1 more source
Food-related illness and death in the United States.
To better quantify the impact of foodborne diseases on health in the United States, we compiled and analyzed information from multiple surveillance systems and other sources.
P. Mead +7 more
semanticscholar +2 more sources
Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines
Sorafenib, a protein kinase inhibitor approved for the treatment of hepatocellular carcinoma and advanced renal cell carcinoma, has been repeatedly reported to induce ferroptosis by possibly involving inhibition of the cystine/glutamate antiporter, known
Jiashuo Zheng +5 more
doaj +1 more source
Life at the end of life: beliefs about individual life after death and "good death" models - a qualitative study [PDF]
BACKGROUND: Different ideas of "good death" may influence the effectiveness of end-of-life care in patients with different ethos. This study aimed to identify the influence of believing in individual life after death on "good death" models. METHODS: Semi
Boeri, Paolo +3 more
core +3 more sources
Crib death, or sudden infant death syndrome (SIDS), is the most frequent form of death in the first year of life, striking one baby in every 1,700–2,000.
Giulia Ottaviani
doaj +1 more source
Structural imaging biomarkers of sudden unexpected death in epilepsy. [PDF]
Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who ...
Balestrini, Simona +12 more
core +3 more sources
Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]
BackgroundVertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Enke, Raymond A +5 more
core +8 more sources

