Results 31 to 40 of about 103,574 (304)

Respiratory Involvement in Patients with Neuromuscular Diseases: A Narrative Review

Pulmonary Medicine, 2019
Respiratory muscle weakness is a major cause of morbidity and mortality in patients with neuromuscular diseases (NMDs). Respiratory involvement in NMDs can manifest broadly, ranging from milder insufficiency that may affect only sleep initially to severe
Athanasios Voulgaris, Maria Antoniadou, Michalis Agrafiotis, Paschalis Steiropoulos   +3 more
doaj   +1 more source

Congenital acinar dysplasia: a lethal entity

Autopsy and Case Reports, 2019
Congenital acinar dysplasia is a lethal, developmental lung malformation resulting in neonatal respiratory insufficiency. This entity is characterized by pulmonary hypoplasia and arrest in the pseudoglandular stage of development, resulting in the ...
Sabrina Oneto, Robert J. Poppiti
doaj   +1 more source

Minute ventilation measurement using Plethysmographic Imaging and lighting parameters [PDF]

arXiv, 2022
Breathing disorders such as sleep apnea is a critical disorder that affects a large number of individuals due to the insufficient capacity of the lungs to contain/exchange oxygen and carbon dioxide to ensure that the body is in the stable state of homeostasis.
arxiv  

Outcome of Paraquat Poisoned Patients Treated with a Commonly Used Therapeutic Flowchart: A Case Series [PDF]

Asia Pacific Journal of Medical Toxicology, 2015
Background: Paraquat poisoning is a medical emergency challenge due to its inherent severe toxicity and unavailability of specific antidote for it. In this paper, a series of patients who were treated according to a commonly used treatment flowchart are ...
Devanur Rajashekhara Murthy Mahadeshwara Prasad, Abhilash Chennabasappa   +1 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

First experience of the usage of peripheral extracorporeal membrane oxygenation in a child with severe respiratory insufficiency

Український журнал серцево-судинної хірургії, 2019
Extracorporeal membrane oxygenation (ECMO) is a life-supporting technique in the treatment of severe cardiac and respiratory insufficiency. It is based on the prolonged extracorporeal blood circulation.
V. Safonov, R. Sekelyk, A. Vysotskyi, A. Avetyan, O. Motrechko, I. Yemets   +5 more
doaj   +1 more source

Respiratory insufficiency correlated strongly with mortality of rodents infected with West Nile virus. [PDF]

PLoS ONE, 2012
West Nile virus (WNV) disease can be fatal for high-risk patients. Since WNV or its antigens have been identified in multiple anatomical locations of the central nervous system of persons or rodent models, one cannot know where to investigate the actual ...
John D Morrey, Venkatraman Siddharthan, Hong Wang, Jeffery O Hall   +3 more
doaj   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Hereditary myopathy with early respiratory failure: case report

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023
Background Hereditary myopathy with early respiratory failure (HMERF) is a rare myopathy that affects respiratory muscles in the early course of the disease leading to respiratory insufficiency. It is caused by mutation in titin (TTN) gene.
Milutin Petrovic, Milos Ratinac, Stojan Peric, Romana Pusica, Ivan Cekerevac   +4 more
doaj   +1 more source

Quantification and dosimetric impact of intra‐fractional bladder changes during CBCT‐guided online adaptive radiotherapy for pelvic cancer treatments

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study quantitatively evaluates bladder changes and their dosimetric impact during the on‐couch adaptive process on a commercial CBCT‐based online adaptive radiotherapy (CT‐gART) platform. Methods Data from 183 fractions of ten patients receiving online ART for pelvic cancers were analyzed retrospectively.
Ingrid Valencia Lozano, Elizabeth Buss, Catherine S. Spina, David P. Horowitz, Lisa A. Kachnic, Michael Price, Yi‐Fang Wang, Reshma Munbodh   +7 more
wiley   +1 more source