Results 31 to 40 of about 4,189 (126)

Art/Sci Nexus, 9 Evenings Revisited [PDF]

open access: yes, 2016
Following the exhibition of Hybrid Bodies at KKW in 2016 Andrew Carnie and I were invited back to act as mentors to a group of young artists and scientists from all over Europe undertaking a week long workshop designed to lead to new art/science ...
Carnie, Andrew   +3 more
core  

Russian Concept of War, Management and Use of Military Power : Conceptual Change [PDF]

open access: yes, 2022
This publication consists primarily of articles presented in the annual Russia Seminar 2022 organised by the Department of warfare of the Finnish National Defence University (FNDU) and titled as “Russian Concept of War, Management and Use of Military ...

core  

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

THE INDETERMINATE PRESENT: AN ESSAY ON QUANTUM MECHANICS AND THE OPEN FUTURE [PDF]

open access: yes, 2020
The dissertation is a defense of the following conditional claim: if there are objective collapses of the wavefunction, then the future is genuinely open. Although this is no radically new idea, the strategy I shall use to defend it is a new one.
C. Mariani
core   +1 more source

Dual‐Locking the SARS‐CoV‐2 Spike Trimer: An Amphipathic Molecular “Bolt” Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition

open access: yesAdvanced Science, EarlyView.
A new amphipathic molecule, S416 is discovered, that locks the SARS‐CoV‐2 spike protein in its closed state, blocking viral entry. S416 acts as a molecular bolt, binding six sites: three between adjacent RBDs and three connecting NTDs to RBDs. This dual‐locking mechanism stiffens the spike structure and reduces its flexibility.
Shiliang Li   +21 more
wiley   +1 more source

Closed subsets of a CAT(0) 2-complex are intrinsically CAT(0) [PDF]

open access: yesAlgebr. Geom. Topol. 21 (2021) 1723-1744, 2019
Let k be at most 0, and let X be a locally-finite CAT(k) polyhedral 2-complex X, each face with constant curvature k. Let E be a closed, rectifiably-connected subset of X with trivial first singular homology. We show that E, under the induced path metric, is a complete CAT(k) space.
arxiv   +1 more source

DiffMC‐Gen: A Dual Denoising Diffusion Model for Multi‐Conditional Molecular Generation

open access: yesAdvanced Science, EarlyView.
DiffMC‐Gen, a dual‐diffusion model for 2D and 3D molecular generation, simultaneously optimizes multiple key objectives across the drug design process, enabling the generation of novel, target‐specific small‐molecule ligands with high therapeutic potential.
Yuwei Yang   +7 more
wiley   +1 more source

Growing Schrödinger's cat states by local unitary time evolution of product states

open access: yesPhysical Review Research
We envisage many-body systems described by quantum spin-chain Hamiltonians featuring a trivial separable eigenstate. For generic Hamiltonians, such a state represents a quantum scar.
Saverio Bocini, Maurizio Fagotti
doaj   +1 more source

MdDSK2a‐Like‐MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition

open access: yesAdvanced Science, EarlyView.
Under cold stress, MdDSK2a‐like is degraded via the 26S proteasome pathway, thereby alleviating the degradation of MdMTA induced by the 26S proteasome and autophagy pathways mediated by MdDSK2a‐like. The accumulated MdMTA increases the m6A levels of cold‐responsive genes, thereby contributing to increased ROS detoxification, deposition of cell wall, as
Nan Hou   +18 more
wiley   +1 more source

Is Schrödinger's cat dead oa alive?

open access: yesZagadnienia Filozoficzne w Nauce, 2005
The Schrödinger's Cat paradox was proposed in 1935 by Edwin Schrodinger, one of the founders of quantum mechanics, as an attempt to visualize the macroscopic realization of a quantum superposition state.
Wojciech Grygiel
doaj  

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