Results 31 to 40 of about 149 (147)

“Sorting Things out”: A Scoping Review of Sexual Homicide Typologies

open access: yesBehavioral Sciences &the Law, EarlyView.
ABSTRACT Sexual homicides are complex crimes that have been the focus of numerous classification systems aimed at aiding investigations, understanding offender behavior, and informing treatment plans. Over the past 25 years, a variety of typologies have been developed to categorize these offenses.
Eric Beauregard, Julien Chopin
wiley   +1 more source

Hijacking the MDM2 E3 Ligase with novel BRD4‐Targeting PROTACs in Pancreatic Cancer Cells

open access: yesChemBioChem, Accepted Article.
The phenotypic effect induced by a Proteolysis‐Targeting Chimera (PROTAC) can depend on several factors, including the E3 ligase recruited. For the discovery of a first‐in‐class PROTAC for a target of interest, the E3 ligases commonly hijacked remain the Von Hippel‐Lindau (VHL) and Cereblon (CRBN) since potent and accessible ligands are readily ...
Mihaela Ficu   +4 more
wiley   +1 more source

The Prevalence of Narcissistic Vulnerability in Men in English Prisons After Criminal Conviction for Stalking

open access: yesCriminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background In earlier research with prisoners, we observed that convicted stalkers had skill deficits in interpreting their experiences of stalking and their motivations for it, suggesting narcissistic vulnerability. Aims Our primary aim was to explore the prevalence of narcissistic vulnerability in men serving a prison sentence in England and
Gemma Dearn   +3 more
wiley   +1 more source

Physician-assisted suicide

open access: yesBMJ, 1998
Ed Robert F Weir Indiana University Press, £24.95, pp 266 ISBN 0 253 33282 6 During the first Dutch study into euthanasia and other end-of-life decisions (for the Remmelink committee in 1991), we asked doctors involved in euthanasia cases why they chose euthanasia instead of assisted suicide and vice versa.
openaire   +4 more sources

Euthanasia, Suicide and Physician-Assisted Suicide An Impression [PDF]

open access: yesInternational Journal of Trend in Scientific Research and Development, 2018
The most painful loss in a person's existence would be the loss of his wholesome health. Each and every being in this world is living a competitive life in order for their survival and to defeat death. But, astonishingly, some people seek their own death and request other fellow beings for their end.
Swaraj L. K, Yazhini. R
openaire   +2 more sources

Practicum Students’ Anticipatory Thoughts About Challenging Client Situations

open access: yesCounselor Education and Supervision, EarlyView.
ABSTRACT Practicum students’ anxiety as they envision seeing “real” clients can impede their self‐efficacy and in‐session functioning. To explore how anticipatory stress and coping theory might help better support them, we used CQR‐M to code students’ (n = 42) immediate thoughts and reactions to three challenging client situations before and after ...
L. DiAnne Borders   +2 more
wiley   +1 more source

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

open access: yesCytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah   +2 more
wiley   +1 more source

Deep Phenotyping of the Broader Autism Phenotype in Epilepsy: A Transdiagnostic Marker of Epilepsy and Autism Spectrum Disorder

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective We conducted deep and minimal phenotyping of the broader autism phenotype (BAP) in people with epilepsy (PWE) and compared its expression with published rates in the general population and relatives of individuals with autism spectrum disorder (ASD‐relatives).
Annie E. Richard   +2 more
wiley   +1 more source

Suicidal behavior and assisted suicide in dementia

open access: yesInternational Psychogeriatrics, 2015
Concerns about suicide risk in people with dementia have been increasing in recent years along with a discourse about rational suicide and assisted suicide.A systematic narrative literature review of suicidal behavior and assisted suicide in persons with dementia.Most studies that have examined the spectrum of suicidal ideation, attempted suicide and ...
Brian M. Draper, Henry Brodaty
openaire   +2 more sources

All in the Name of Artificial Intelligence: A Commentary on Linardon (2025)

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Artificial Intelligence (AI) is being rapidly integrated into healthcare, but Linardon et al. reveal a troubling gap between what AI actually is, its capabilities, and the patients' and clinicians' perceptions of it—equating AI solely with large language models.
Pia Burger, Sreejita Ghosh
wiley   +1 more source

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