Results 31 to 40 of about 13,789 (243)

Safety and Efficacy of Low-Dose Tirofiban Combined With Intravenous Thrombolysis and Mechanical Thrombectomy in Acute Ischemic Stroke: A Matched-Control Analysis From a Nationwide Registry

Frontiers in Neurology, 2021
Purpose: Tirofiban administration to acute ischemic stroke patients undergoing mechanical thrombectomy with preceding intravenous thrombolysis remains controversial.
Gaoting Ma, Shuo Li, Baixue Jia, Dapeng Mo, Ning Ma, Feng Gao, Xiaochuan Huo, Gang Luo, Anxin Wang, Yuesong Pan, Ligang Song, Xuan Sun, Xuelei Zhang, Liqiang Gui, Cunfeng Song, Ya Peng, Jin Wu, Shijun Zhao, Junfeng Zhao, Zhiming Zhou, Zhongrong Miao   +20 more
doaj   +1 more source

Factors affecting the outcomes of tirofiban after endovascular treatment in acute ischemic stroke: Experience from a single center

CNS Neuroscience & Therapeutics, 2023
To investigate the predicted factors influencing the outcomes in acute ischemic stroke (AIS) patients who received tirofiban after endovascular treatment (EVT) and the optimal administration of tirofiban.
Yuan Wang, Hongrui Ma, Qihan Zhang, Feiyang Jin, Yi Xu, Qingfeng Ma, X. Ji   +6 more
semanticscholar   +1 more source

Can Tirofiban Improve the Outcome of Patients With Acute Ischemic Stroke: A Propensity Score Matching Analysis

Frontiers in Neurology, 2021
Objective: To evaluate the efficacy and safety of tirofiban for patients with acute ischemic stroke (AIS), especially posterior circulation stroke (PCS).Methods: We enrolled consecutive patients with AIS who suffered large artery occlusion (LAO) and ...
Lingxin Cai, Xiaobo Yu, Jun Yu, Jing Xu, Liang Xu, Chenhan Ling, Min Lou, Cheng Yu, Cong Qian   +8 more
doaj   +1 more source

Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation

Platelets, 2022
We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry.
Martina Aguiar Bucsai, Christian Idel, Barbara Wollenberg, Christine Mannhalter, Admar Verschoor   +4 more
doaj   +1 more source

Intravenous tirofiban following successful reperfusion in intracranial large artery atherosclerotic stroke: A secondary analysis of a randomized clinical trial

Annals of Clinical and Translational Neurology, 2023
This study aimed to investigate whether treatment with adjunct intravenous tirofiban is associated with improved outcomes following successful reperfusion in patients with intracranial atherosclerotic stroke.
Jiacheng Huang, W. Kong, Chang Liu, Jiaxing Song, Jie Yang, C. Yue, Linyu Li, Jinrong Hu, Yan Tian, Z. Peng, Chang-Yu Guo, Dahong Yang, Xiang Liu, J. Miao, Xiao Zhang, Fengli Li, J. Saver, W. Zi   +17 more
semanticscholar   +1 more source

Efficacy and safety of tirofiban in patients with acute ischemic stroke without large-vessel occlusion and not receiving intravenous thrombolysis: A randomized controlled open-label trial

Journal of Neurorestoratology, 2022
ObjectiveTo investigate the effectiveness and safety of tirofiban in patients with acute ischemic stroke (AIS) without large-vessel occlusions and not receiving intravenous thrombolysis.MethodsOverall, 267 cases were included in the study (134 cases in ...
Yongpeng Yu, Yali Zheng, Xia Dong, Xiaohong Qiao, Yu Tao   +4 more
doaj   +1 more source

Morphine Analgesia Pre-PPCI Is Associated with Prothrombotic State, Reduced Spontaneous Reperfusion and Greater Infarct Size [PDF]

, 2017
Schattauer GmbH Stuttgart.The emergency management of ST-elevation myocardial infarction (STEMI) involves treatment with dual-antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PPCI). Pain is generally treated with opiates, which
Farag, Mohamed, Gorog, Diana A, Spinthakis, Nikolaos, Srinivasan, Manivannan, Sullivan, Keith, Wellsted, David   +5 more
core   +1 more source

The Efficacy and Safety of Tirofiban Use in Endovascular Thrombectomy for Intravenous Thrombolysis Applicable Patients with Large Vessel Occlusion Stroke—a Post Hoc Analysis from the Direct-MT Trial

Cardiovascular and Interventional Radiology, 2023
Purpose The purpose of the study was to evaluate the efficacy and safety of tirofiban use in endovascular thrombectomy for intravenous thrombolysis applicable patients of large vessel occlusion stroke with data from Direct-MT trial. Materials and Methods
Yingying Zhang, Ping Zhang, Anyang Tao, Xinliang Wang, Jiangxian Ying, Zhimin Wang, Pengfei Yang, Yongwei Zhang, Lei Zhang, Zifu Li, Meng Zhang, Chenghua Xu, Jianmin Liu   +12 more
semanticscholar   +1 more source

Glycoprotein IIb/IIIa Inhibitors Use and Outcome after Percutaneous Coronary Intervention for Non-ST Elevation Myocardial Infarction [PDF]

, 2014
Aims. We investigate the effect of glycoprotein IIb/IIIa (GP IIb/IIIa) inhibitors on long-term outcomes following percutaneous coronary intervention (PCI) after non-ST elevation myocardial infarction (NSTEMI). Meta-analyses indicate that these agents are
Antoniou, S, Gallagher, S, Howard, JP, Jones, DA, Knight, C, Mathur, A, Rathod, K, Weerackody, R, Wragg, A, Wright, P   +9 more
core   +4 more sources

Glycoprotein Ib activation by thrombin stimulates the energy metabolism in human platelets [PDF]

, 2017
Thrombin-induced platelet activation requires substantial amounts of ATP. However, the specific contribution of each ATP-generating pathway i.e., oxidative phosphorylation (OxPhos) versus glycolysis and the biochemical mechanisms involved in the thrombin-
A Archiche, A Ferreta, A Kasirer-Friede, A Lechi, A Marín-Hernández, AI Schafer, AJM Verhoeven, AM Amorini, AN Sveshnikova, AR Gear, Christian Schulz, D Banerjee, DA Slatter, E De Candia, E De Candia, F Adam, F Sinigaglia, G Solsau, GN Bijur, H Kilkson, HU Bergmeyer, I Fisher, I Hernández-Reséndiz, Ileana Hernández-Reséndiz, J Deprez, JRS Day, JW Akkerman, JY Jang, KS Authi, L Brass, LR Sorbara, M Baggiolini, Manuel Gutiérrez-Aguilar, MH Rider, MR Wardell, MY Shen, N Cardenes, N Corona de la Peña, NM Bressler, Norma Corona de la Peña, RA Nakashima, RL Elstrom, RM Denton, RW Moreadith, S Kim, S Offermans, S Ravi, S Rodríguez-Enríquez, S Zharikov, Sara Rodríguez-Enríquez, SI Obydennyy, T Sabo, V Vasta, Y Dobrydneva, Y Dobrydneva, ZP Shaik, Álvaro Marín-Hernández   +56 more
core   +4 more sources