Results 31 to 40 of about 1,351,970 (298)

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Addressing the quality of paediatric primary care: health worker and caregiver perspectives from a process evaluation of PACK child, a health systems intervention in South Africa

BMC Pediatrics, 2021
Background The WHO’s Integrated Management of Childhood Illness (IMCI) has resulted in progress in addressing infant and child mortality. However, unmet needs of children continue to present a burden upon primary healthcare services.
Robyn Curran, Jamie Murdoch, Max Bachmann, Eric Bateman, Ruth Cornick, Sandra Picken, Makhosazana Lungile Simelane, Lara Fairall   +7 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

DEFINITION OF TRANSLATION, TRANSLATION STRATEGY, TRANSLATION PROCEDURE, TRANSLATION METHOD, TRANSLATION TECHNIQUE, TRANSLATION TRANSFORMATION

InterConf, 2021
In modern linguistics, one of the current topics is the study of the relationships between languages, as one of the main means of transmission of meanings and the socio-cultural reality. Among the many challenges studied by the modern linguistics, an important place is the study of the linguistic aspects of cross-language speech activity, which is ...
openaire   +2 more sources

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Frailty, delirium and hospital mortality of older adults admitted to intensive care: the Delirium (Deli) in ICU study

Critical Care, 2020
Background Clinical frailty among older adults admitted to intensive care has been proposed as an important determinant of patient outcomes. Among this group of patients, an acute episode of delirium is also common, but its relationship to frailty and ...
David Sanchez, Kathleen Brennan, Masar Al Sayfe, Sharon-Ann Shunker, Tony Bogdanoski, Sonja Hedges, Yu Chin Hou, Joan Lynch, Leanne Hunt, Evan Alexandrou, Manoj Saxena, Simon Abel, Ramanathan Lakshmanan, Deepak Bhonagiri, Michael J. Parr, Anders Aneman, Danielle Ni Chroinin, Kenneth M. Hillman, Steven A. Frost   +18 more
doaj   +1 more source

Technical Infrastructures of Historical Translation Knowledge: A Call for the use of the Digital Library and Bibliography of Literature in Translation

Chronotopos, 2022
Editorial in English and German on the technical infrastructures relevant for translation history. The editors share an invitation to make use of the Digital Library and Bibliography of Literature in Translation (DLBT) and discuss the needs of ...
Larisa Schippel, Julia Richter, Tomasz Rozmyslowicz , Stefanie Kremmel   +3 more
doaj   +1 more source

Translated in Translation Studies

transLogos Translation Studies Journal, 2018
The current article aims to test conceptual borders and explanatory potential of intralingual translation. It takes up from the findings of the author’s previous research questioning differing approaches toward intralingual translation published in a single multiauthor volume showcasing Translation Studies research in Turkey.
openaire   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Current landscape of mRNA technologies and delivery systems for new modality therapeutics

Journal of Biomedical Science
Realizing the immense clinical potential of mRNA-based drugs will require continued development of methods to safely deliver the bioactive agents with high efficiency and without triggering side effects.
Ruei-Min Lu, Hsiang-En Hsu, Ser John Lynon P. Perez, Monika Kumari, Guan-Hong Chen, Ming-Hsiang Hong, Yin-Shiou Lin, Ching-Hang Liu, Shih-Han Ko, Christian Angelo P. Concio, Yi-Jen Su, Yi-Han Chang, Wen-Shan Li, Han-Chung Wu   +13 more
doaj   +1 more source