Results 31 to 40 of about 3,588,358 (362)

School-Based Deworming Program Yields Small Improvement in Growth of Zanzibari School Children After one Year. [PDF]

, 1997
Efficacy trials of antihelminthic therapies conducted in Africa have reported improvements in children's growth, but nutritional evaluations of large-scale deworming programs are lacking.
Albonico, Albonico, Diggle, Ferguson, Hababu M. Chwaya, James M. Tielsch, Kruger, Latham, Lawless, Lorenzo Savioli, Marco Albonico, Must, Must, Rebecca J. Stoltzfus, Renganathan, Savioli, Savioli, Shiff, Stephenson, Stephenson, Stephenson, Stephenson, Stoltzfus, Stoltzfus, Warren, World Bank, World Health Organization, World Health Organization, World Health Organization, World Health Organization Expert Committee   +29 more
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Benefit of viral load testing for confirmation of immunological failure in HIV patients treated in rural Malawi. [PDF]

, 2011
Objective  Viral load testing is used in the HIV programme of Chiradzulu, Malawi, to confirm the diagnosis of immunological failure to prevent unnecessary switching to second-line therapy.
Badri, Bisson, Calmy, Ekouevi, Ferradini, Kantor, Keiser, Lebon, Mee, Moore, Murri, Reynolds, van Oosterhout, World Health Organization, World Health Organization   +14 more
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Evaluation of the electronic Early Warning and Response Network (EWARN) system in Somalia, 2017–2020

Conflict and Health, 2022
Background In 2008, Somalia introduced an electronic based Early Warning Alert and Response Network (EWARN) for real time detection and response to alerts of epidemic prone diseases in a country experiencing a complex humanitarian situation.
Mutaawe Lubogo, Mary Joan Karanja, Rennatus Mdodo, Sherein Elnossery, Ali Abdirahman Osman, Abdulkadir Abdi, Evans Buliva, Muhammad Tayyab, Omar Abdulle Omar, Mirza Mashrur Ahmed, Solomon Chane Abera, Abdinasir Abubakar, Sk Md Mamunur Rahman Malik   +12 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Analysing the implementation of infection prevention and control measures in health care facilities during the COVID-19 pandemic in the African Region

BMC Infectious Diseases, 2023
Background The declaration of SARS-CoV-2 as a public health emergency of international concern in January 2020 prompted the need to strengthen infection prevention and control (IPC) capacities within health care facilities (HCF).
Landry Kabego, Thierno Balde, Deborah Barasa, Babacar Ndoye, Okou-Bisso Hilde, Tendai Makamure, Guy Ohirweoluhya Mulumeoderwa, Trevor Kanyowa, Rashidatu Fouad Kamara, Boiro Hamadou, Opeayo Ogundiran, Joseph Okeibunor, George Williams, Jayne Byakika Tusiime, Phionah Lynn Atuhebwe, Boniface Oyugi, Elande-Taty Mawanda, Andry Razakamanantsoa, Fiona Braka, Dick Chamla, Abdou Salam Gueye   +20 more
doaj   +1 more source

Preventing Stock-outs of Antimalarial\ud Drugs in sub-Saharan Africa:Novartis’s SMS for Life [PDF]

, 2013
Malaria is curable. Although highly effective antimalarial drugs are available (up to 96% effective in the case of artemisinin-lumefantrine fixed-dose combinations), widespread stock-outs lead to deaths on a daily basis.
World Health Organization , (WHO)
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