Results 41 to 50 of about 24,814 (247)

Analgesic Effects of Repetitive Transcranial Magnetic Stimulation at Different Stimulus Parameters for Neuropathic Pain: A Randomized Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The aim of the present study was to investigate the analgesic effects of repetitive transcranial magnetic stimulation over the primary motor cortex (M1‐rTMS) using different stimulation parameters to explore the optimal stimulus condition for treating neuropathic pain.
Nobuhiko Mori, Koichi Hosomi, Asaya Nishi, Satoru Oshino, Haruhiko Kishima, Youichi Saitoh   +5 more
wiley   +1 more source

Analysis of the effects of a tricyclic antidepressant on secondary sleep disturbance induced by chronic pain in a preclinical model.

PLoS ONE, 2020
Chronic pain and sleep have a bidirectional relationship that promotes a vicious circle making chronic pain more difficult to treat. Therefore, pain and sleep should be treated simultaneously.
Hisakatsu Ito, Yoshinori Takemura, Yuta Aoki, Mizuki Hattori, Hideyo Horikawa, Mitsuaki Yamazaki   +5 more
doaj   +1 more source

Modulation of nociception by amitriptyline hydrochloride in the Speke’s hinge‐back tortoise (Kiniskys spekii)

Veterinary Medicine and Science, 2021
Background There are limited studies on the utilization of analgesics in testudines. Management of pain in reptiles is by use of analgesics generally used in other vertebrate species.
Christopher M. Makau, Philemon K. Towett, Klas S.P. Abelson, Titus I. Kanui   +3 more
doaj   +1 more source

A National Study Among Diverse US Populations of Exposure to Prescription Medications with Evidence‐Based Pharmacogenomic Information

Clinical Pharmacology &Therapeutics, EarlyView.
Tailoring pharmacogenomic (PGx) implementation to diverse populations is vital to promoting health equity. We assessed prescriptions for medications with potentially actionable PGx information to identify patient characteristics associated with differential PGx medication exposure.
Loren Saulsberry, Jacob C. Jameson, Robert D. Gibbons, M. Eileen Dolan, Olufunmilayo I. Olopade, Peter H. O’Donnell   +5 more
wiley   +1 more source

Amitriptyline for migraine prophylaxis in adolescents

Paediatrica Indonesiana, 2011
headaches in children and adolescents. Amitriptyline efficacy as a prophylactic treatment for migraine in adults has been widely studied, but there is limited data on its use in children and adolescents.
Yazid Dimyati, Astri Nurhayati Zulkifli, Pranoto Trilaksono, Johannes H. Saing, Bistok Saing   +4 more
doaj   +1 more source

Changing trends in anabolic‐androgenic steroid use within Scottish prisons: Detection, prevalence, and quantitation

Drug Testing and Analysis, EarlyView.
This study reports the qualitative and quantitative detection of anabolic‐androgenic steroids (AASs) in seized samples from prisons. Since 2022 there has been an increase in AAS detections with oxymetholone the most prevalent AAS, followed by metandienone, methyltestosterone, and oxandrolone.
Caitlyn Norman, Richard L. Harries, Robert Reid, Lorna A. Nisbet, Niamh Nic Daéid   +4 more
wiley   +1 more source

Multianalyte Approach—Including Automated Preparation of Calibrators—for Validated Quantification of 82 Drugs in Whole Blood by Liquid Chromatography–Tandem Mass Spectrometry

Drug Testing and Analysis, EarlyView.
In forensic bioanalysis, often multianalyte approaches are used given their increased effectiveness but can be difficult to develop and maintain in the laboratory, for example, in terms of calibrator solution preparation. A fast, simple, and robust liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the quantification of 82 classic ...
Andrea E. Steuer, Maja Keller, Thomas Kraemer, Sandra N. Poetzsch   +3 more
wiley   +1 more source

Rapid Analytical Method for Quantification of Gamma‐Hydroxybutyrate (GHB) in Hair by UPLC‐MS/MS

Drug Testing and Analysis, EarlyView.
A rapid and simple UPLC‐MS/MS method for quantification of GHB in 10 mg of hair was developed. The method was satisfactorily validated, showing a linear range of 0.5–50 ng/mg, which allows us to quantify endogenous and exogenous GHB concentrations.
Miriam Blanco‐Ces, Ana de‐Castro‐Rios, Angela Lopez‐Rabuñal, Maria Cobo‐Golpe, Angelines Cruz, Elena Lendoiro   +5 more
wiley   +1 more source

Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study

Arquivos de Neuro-Psiquiatria, 2014
To compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine. Method Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were ...
Michelle Dias Santos Santiago, Deusvenir de Souza Carvalho, Alberto Alain Gabbai, Mariana Machado Pereira Pinto, Andrea Regina Correa Moutran, Thais Rodrigues Villa   +5 more
doaj   +1 more source

Comparing the efficacy and safety of duloxetine and amitriptyline in the treatment of fibromyalgia: overview of systematic reviews

Advances in Rheumatology, 2020
Background Duloxetine and amitriptyline are antidepressants used in the treatment of fibromyalgia. In published systematic reviews, there is no agreement about which drug is more effective and safer.
Áurea Dias de Farias, Luciana Eberle, Tânia Alves Amador, Tatiane da Silva Dal Pizzol   +3 more
doaj   +1 more source