Results 41 to 50 of about 22,631 (229)

Oral Provocation Testing in Cutaneous Adverse Drug Reactions to Antiretroviral and Antitubercular Therapy: A Study at a Tertiary Care Hospital in South India

Journal of the International Association of Providers of AIDS Care, 2018
Aim: To collect data pertaining to oral drug provocation testing (DPT) in hospitalized patients with antiretroviral (ARV)/antitubercular agent–induced rashes.
Sowmya Kaimal MBBS, MD, Jithendriya Madhukara MBBS, DVD, DNB   +1 more
doaj   +1 more source

Data-mining of potential antitubercular activities from molecular ingredients of traditional Chinese medicines [PDF]

, 2014
Background. Traditional Chinese medicine encompasses a well established alternate system of medicine based on a broad range of herbal formulations and is practiced extensively in the region for the treatment of a wide variety of diseases. In recent years,
Baell, Bouckaert, Chang, Chen, Chen, Chen, Cheng, Choi, DiMasi, Fang, Han, Hann, Hu, Huth, Iinuma, Issabeagloo, Jaiswal, Jamal, Jamal, Jiang, Kurti, Li, Li, Li, Liu, Liu, Lu, Melville, Merget, Mohamed Saleem, Nader, Nair, Normile, Ooi, O’Boyle, Periwal, Periwal, Qiu, Rani, Sato, Schierz, Schneidman-Duhovny, Shah, Silva, Singla, Su, Sucher, Thattakudian Sheik Uduman, Udino, Vasanthanathan, Vert, Wagner, Wang, Wang, Wen, Xue, Yew, Zhang   +57 more
core   +1 more source

The challenge of managing extensively drug-resistant tuberculosis at a referral hospital in the state of São Paulo, Brazil: a report of three cases [PDF]

Jornal Brasileiro de Pneumologia, 2015
Here, we report the cases of three patients diagnosed with extensively drug-resistant tuberculosis and admitted to a referral hospital in the state of São Paulo, Brazil, showing the clinical and radiological evolution, as well as laboratory test results,
Marcos Abdo Arbex, Hélio Ribeiro de Siqueira, Lia D'Ambrosio, Giovanni Battista Migliori   +3 more
doaj   +3 more sources

Colo‐appendico‐duodenal fistula: Rare presentation of extrapulmonary tuberculosis

Clinical Case Reports, 2021
A colo‐appendico‐duodenal fistula is a rare occurrence that results from extrapulmonary tuberculosis (TB) complications, especially in the endemic region.
David Eng Yeow Gan, Rohamini Sibin, Alvin Oliver Payus, Firdaus Hayati   +3 more
doaj   +1 more source

MEPicides: Potent antimalarial prodrugs targeting isoprenoid biosynthesis [PDF]

, 2017
The emergence of Plasmodium falciparum resistant to frontline therapeutics has prompted efforts to identify and validate agents with novel mechanisms of action. MEPicides represent a new class of antimalarials that inhibit enzymes of the methylerythritol
Brothers, Robert C, Dowd, Cynthia S, Edwards, Rachel L, Hruz, Paul W, Kraft, Thomas E, Maron, Maxim I, Odom John, Audrey R, Tsang, Patricia S, Wang, Xu, Williamson, Kim C, Ziniel, Peter D   +10 more
core   +2 more sources

New Conjugates of Quinoxaline as Potent Antitubercular and Antibacterial Agents [PDF]

International Journal of Medicinal Chemistry, 2016
Considering quinoxaline as a privileged structure for the design of potent intercalating agents, some new sugar conjugates of quinoxaline were synthesized and characterized by IR, 1HNMR, 13C NMR, and mass spectral data. In vitro testing for antitubercular and antimicrobial activities was performed against Mycobacterium tuberculosis H37Rv and some ...
Ramalingam Peraman, Rajendran Kuppusamy, Sunil Kumar Killi, Y. Padmanabha Reddy   +3 more
openaire   +3 more sources

Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides

Chemistry Central Journal, 2018
Background The study describes the synthesis, characterization, in vitro antimicrobial and anticancer evaluation of a series of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamide derivatives. The synthesized derivatives were also assessed
Snehlata Yadav, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Abhishek Mathur, Balasubramanian Narasimhan   +6 more
doaj   +1 more source

Antimycobacterial activity of peptide conjugate of pyridopyrimidine derivative against Mycobacterium tuberculosis in a series of in vitro and in vivo models [PDF]

, 2015
New pyridopyrimidine derivatives were defined using a novel HTS in silico docking method (FRIGATE). The target protein was a dUTPase enzyme (EC 3.6.1.23; Rv2697) which plays a key role in nucleotide biosynthesis of Mycobacterium tuberculosis (Mtb). Top
Bacsa, B., Balka, Gy., Bősze, Szilvia, Fodor, K., Grolmusz, V., Horváti, Kata, Hudecz, Ferenc, Kiss, É., Mező, Gábor, Rusvai, M., Szabó, N., Vértessy G., Beáta   +11 more
core   +1 more source

PYRAZOLINES AS POTENT ANTITUBERCULAR AND CYTOTOXIC AGENTS

Asian Journal of Pharmaceutical and Clinical Research, 2017
Objective: Pyrazolines are known to exhibit different biological and pharmacological properties such as anticancer, antibacterial, antifungal and antitubercular activities. Chalcones with an enone group between two aromatic rings exhibit remarkable pharmacological activities such as antiinflammatory, antibacterial, antitumor, antifungal, and ...
Ishwar Bhat K, Abhishek Kumar
openaire   +3 more sources

Design, Facile Synthesis and Characterization of Dichloro Substituted Chalcones and Dihydropyrazole Derivatives for Their Antifungal, Antitubercular and Antiproliferative Activities

Molecules, 2020
Infectious diseases caused by fungi and mycobacteria pose an important problem for humankind. Similarly, cancer is one of the leading causes of death globally.
Afzal B. Shaik, Richie R. Bhandare, Srinath Nissankararao, Zehra Edis, N. Ravikiran Tangirala, Shaik Shahanaaz, M. Mukhlesur Rahman   +6 more
doaj   +1 more source