Results 41 to 50 of about 102,755 (260)

About the neurolinguistics of the implicatures: abstract of a study

Arquivos de Neuro-Psiquiatria, 1989
Taking into account recent data on linguistics of production and comprehension in aphasia, a protocol was executed including the several types of implicatures.
Juliano Luís Fontanari
doaj   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

Advanced Science, EarlyView.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu, An Shao, Bingtao Guan, Ziyao Luo, Weiyi Lai, Xiaoling Huang, Jun Liu, Jie Yan, Huimin Li, Xiangji Pan, Jiawei Wang, Zichang Su, Yih Chung Tham, Jie Yang, Haotian Lin, Juan Ye, Hongxia Xu, Jian Wu   +17 more
wiley   +1 more source

Enrollment, retention, and strategies for including disadvantaged populations in randomized controlled trials: a systematic review protocol

Systematic Reviews, 2021
Background Many randomized controlled trials fail to reach their target sample size. When coupled with the omission and underrepresentation of disadvantaged groups in randomized controlled trials, many trials fail to obtain data that accurately ...
Abigail LaPlante, Renata W. Yen, Talia Isaacs, Joanna Crocker, Zsofia Demjen, Danielle Schubbe, Alice M. Kennedy, Jaclyn Engel, Nancy O’Brien, Carla Richters, Marie-Anne Durand   +10 more
doaj   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

A Wireless, Battery‐Free Artificial Throat Patch with Deep Learning for Emotional Speech Recognition

Advanced Science, EarlyView.
In this work, Xu and co‐workers develop a wireless, battery‐free artificial throat patch system (ATPS) consisting of a carbon nanotube‐based thin‐film strain sensor and a miniaturized flexible printed circuit board, to enable real‐time sensing of throat signals.
Bingxin Xu, Guanming Lin, Xiaohui Hong, Chuting Liu, Xinyi Qu, Kangjian Jiao, Lei Zhang, Bingzhe Xu, Jun Yan, Yancong Qiao, Xudong Lin   +10 more
wiley   +1 more source

How can creative writing and reading aloud transform the stories told by people in fertility treatment?

2i Revista de Estudos de Identidade e Intermedialidade
This study explores the therapeutic potential of facilitated creative writing for people undergoing fertility treatment. Against the backdrop of a fertility crisis in Denmark and the Western world, the research investigates how narrative practices can ...
Andrea Koefoed Friedrichsen, Anette Søgaard Nielsen, Anders Juhl Rasmussen   +2 more
doaj   +1 more source

Comprehension of idiomatic expressions by Russian speaking typically developing children [PDF]

Psychology in Russia: State of Art, 2017
Background. The ability to understand idiomatic expressions begins to develop at an early age. However, such skill is not achieved within the same age and at the same pace in children speaking di erent languages. Objective.
Eliseeva N.N., Guts E.N., Marini A.
doaj   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

Processing of Scene-Grammar Inconsistencies in Children with Developmental Language Disorder—Insights from Implicit and Explicit Measures

Brain Sciences
Background/Objectives: Developmental language disorders (DLD) are often associated with co-occurring neurodevelopmental difficulties, including attentional or social–emotional problems.
Daniela Bahn, Dilara Deniz Türk, Nikol Tsenkova, Gudrun Schwarzer, Melissa Le-Hoa Võ, Christina Kauschke   +5 more
doaj   +1 more source