Results 41 to 50 of about 5,663,674 (349)

DRUGS EFFICIENCY AND SAFETY: THE ROLE OF PHARMACEUTICAL INDUSTRY

open access: yesРациональная фармакотерапия в кардиологии, 2015
Relationships of pharmaceutical industry with medical science and practice are analyzed. The influence of pharmaceutical industry on clinical trials, journal publications, governmental organizations, physicians and researchers is discussed.
F. I. Belyalov
doaj   +1 more source

The vicious circle of patient-physician mistrust in China: health professionals' perspectives, institutional conflict of interest, and building trust through medical professionalism.

open access: yesDeveloping World Bioethics, 2017
To investigate the phenomenon of patient-physician mistrust in China, a qualitative study involving 107 physicians, nurses and health officials in Guangdong Province, southern China, was conducted through semi-structured interviews and focus groups.
J. Nie   +6 more
semanticscholar   +1 more source

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

open access: yesPopulation Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

‘Inter-critic’ without a Conflict of Interest

open access: yesCritical Stages, 2011
Ivan Medenica[1] 1296608184 Résumé L’« Intercritique » sans conflit d’intérêt Peut-on être un « intercritique » sans se compromettre ? Ici, Ivan Medenica affirme que la question n’est pas aussi neuve qu’on le pense.
Ivan Medenica
doaj  

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

How does militant violence diffuse in regions? Regional conflict systems in international relations and peace and conflict studies [PDF]

open access: yes, 2011
Regional conflict systems are characterised by their complexity of actors, causes, structural conditions and dynamics. Such complexity poses difficulties to those looking to undertake scientific analysis of the regional dynamics of violence.
Ansorg, Nadine
core   +3 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

STRESS TESTING IS AN IMPORTANT DIAGNOSTIC TOOL IN DETECTING CORONARY ARTERY DISEASE

open access: yesGomal Journal of Medical Sciences, 2015
Among many other causes of death, cardiovascular disease is the most common cause of death in developing countries including Pakistan. Management strategies for cardiovascular disease are constantly developing.
Muhammad Inam Qureshi   +3 more
doaj  

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