Results 41 to 50 of about 218,776 (321)

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Hemodynamic effects of partial ventricular support in chronic heart failure: Results of simulation validated with in vivo data [PDF]

ObjectiveCurrent left ventricular assist devices are designed to provide full hemodynamic support for patients with end-stage failing hearts, but their use has been limited by operative risks, low reliability, and device-related morbidity.
Burkhoff, Daniel, Dowling, Robert, Ferber, Paul, Griffith, Bartley, Litwak, Kenneth, Meyns, Bart, Morley, Deborah, Spence, Paul   +7 more
core   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

Left Ventricular Assist Device Implantation in a Patient with Ventricular Pseudoaneurysm

The Thoracic & Cardiovascular Surgeon Reports, 2022
Background Left ventricular assist device (LVAD) implantation after contained LV rupture (pseudoaneurysm) represents a difficult surgical problem. Case Description We describe the surgical approach for such a patient.
Dejan Radakovic, Kiril Penov, Gülmisal Güder, Ivan Aleksic   +3 more
doaj   +1 more source

Minimally invasive implantation of continuous flow left ventricular assist devices: the evolution of surgical techniques in a single centre experience [PDF]

, 2018
To evaluate the evolution of our surgical experience with the implantation of a continuous flow left ventricular assist device (LVAD), from the original full sternotomy approach to less invasive surgical strategies including mini-sternotomy and/or mini ...
Bejko, Jonida, Bianco, Roberto, Bottio, Tomaso, Carrozzini, Massimiliano, Gerosa, Gino, Gregori, Dario, Guariento, Alvise, Rubino, Maurizio, Tarzia, Vincenzo   +8 more
core   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Stent implantation in a left ventricular assist device

REC: Interventional Cardiology (English Ed.), 2020
Sixty-eight-year-old male patient carrier of one HeartWare left ventricular assist device as destination therapy due to ischemic dilated cardiomyopathy.
Raquel Álvarez Ramos, Luis María Andrés Lalaguna, José Luis Díez Gil   +2 more
doaj   +1 more source

Tattoo Assisted Optical Sensor System for Multimodal Discrete Physiological Sensing

Advanced Healthcare Materials, EarlyView.
Conventional temporary tattoos can be used for improving the speckle imaging signal‐to‐noise ratio and stability of the specifically developed device for capturing skin motion related to physiological activities beneath the skin. This allows for sensing multimodal electrophysiological signals and physiological events from the skin consistent with ...
Zihuan Wu, Ahmad El‐Barbary, David Lafleur, Shuyun Zhuo, Chris Williams, Shideh Kabiri Ameri   +5 more
wiley   +1 more source

Application of Machine Learning in Early Recommendation of Cardiac Resynchronization Therapy [PDF]

arXiv, 2021
Heart failure (HF) is a leading cause of morbidity, mortality, and health care costs. Prolonged conduction through the myocardium can occur with HF, and a device-driven approach, termed cardiac resynchronization therapy (CRT), can improve left ventricular (LV) myocardial conduction patterns.
arxiv  

Left Ventricular Wall Motion Estimation by Active Polynomials for Acute Myocardial Infarction Detection [PDF]

, 2020
Echocardiogram (echo) is the earliest and the primary tool for identifying regional wall motion abnormalities (RWMA) in order to diagnose myocardial infarction (MI) or commonly known as heart attack. This paper proposes a novel approach, Active Polynomials, which can accurately and robustly estimate the global motion of the Left Ventricular (LV) wall ...
arxiv   +1 more source