Results 41 to 50 of about 3,494,763 (310)
Nature Communications, 2020 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Wayne Vuong +13 more
doaj +1 more source
The rapid developments of membrane protein structure biology over the last two decades
BMC Biology, 2023 Membrane protein research has flourished in the past 20 years. Exciting technological innovations in structural biology, including cryoEM single-particle analysis and AI-based protein structure prediction, such as AlphaFold 2, have largely revolutionized
Lan Guan
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes
Nature Communications, 2021 The major light-harvesting systems for photosynthesis in cyanobacteria and red algae are phycobilisomes (PBS). Here, the authors present the cryo-EM structures of two cyanobacterial PBS from Anabaena 7120 and Synechococcus 7002 and discuss their energy ...
Lvqin Zheng +7 more
doaj +1 more source
ABCC6 is a basolateral plasma membrane protein [PDF]
, 2013 RATIONALE:: ABCC6 plays a crucial role in ectopic calcification; mutations of the gene cause pseudoxanthoma elasticum and general arterial calcification of infancy.
Apana, A. +11 more
core +4 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Cornichons: Evolution, AMPA receptor modulation, and emerging roles beyond the nervous system
Brain DisordersCornichons are auxiliary proteins that regulate the functions of AMPA receptors (AMPARs), which mediate fast excitatory transmission in the central nervous system.
Pratibha Bharti +3 more
doaj +1 more source
Structural Biology and Structure–Function Relationships of Membrane Proteins
Biology, 2021 To understand the biological complexity of life, one needs to investigate how biomolecules behave and interact with each other at a molecular level [...]
Isabel Moraes, Andrew Quigley
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Modulation of the ISFET response by an immunological reaction [PDF]
, 1989 A new method is presented for the detection of an immunological reaction in a membrane. Antigens (or antibodies) are taken up in a porous membrane, which covers the gate area of an ISFET. By stepwise changing of the electrolyte concentration, a transient
Bergveld, P. +4 more
core +2 more sources