Results 41 to 50 of about 94,280 (307)

Young children's perspectives of time: New directions for co‐constructing understandings of quality in ECEC

open access: yesBritish Educational Research Journal, EarlyView., 2023
Abstract Children's relationship with time in preschools is an under‐researched area. Young children rarely know how to measure time using a clock, but their experiences of time may contribute to understanding children's well‐being and debates about quality in preschools.
Kristín Dýrfjörð   +3 more
wiley   +1 more source

MADS about MOSS [PDF]

open access: yesPlant Signaling & Behavior, 2009
Classic MIKC-type MADS-box genes (MIKC(c)) play diverse and crucial roles in angiosperm development, the most studied and best understood of which is the specification of floral organ identities. To shed light on how the flower evolved, phylogenetic and functional analyses of genes involved in its ontogeny, such as the MIKC(c) genes, must be undertaken
S D, Singer, Neil W, Ashton
openaire   +2 more sources

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

open access: yesAdvanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu   +14 more
wiley   +1 more source

Autonomous eDNA collection using an uncrewed surface vessel over a 4200‐km transect of the eastern Pacific Ocean

open access: yesEnvironmental DNA
The collection of environmental DNA (eDNA) samples is often laborious, costly, and logistically difficult to accomplish at high frequency in remote locations and over large geographic areas.
Christina Preston   +10 more
doaj   +1 more source

Targeted Sampling by Autonomous Underwater Vehicles

open access: yesFrontiers in Marine Science, 2019
In the vast ocean, many ecologically important phenomena are temporally episodic, localized in space, and move according to local currents. To effectively study these complex and evolving phenomena, methods that enable autonomous platforms to detect and ...
Yanwu Zhang   +11 more
doaj   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

open access: yesAdvanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter   +4 more
wiley   +1 more source

Seasonal and Geographical Transitions in Eukaryotic Phytoplankton Community Structure in the Atlantic and Pacific Oceans

open access: yesFrontiers in Microbiology, 2020
Much is known about how broad eukaryotic phytoplankton groups vary according to nutrient availability in marine ecosystems. However, genus- and species-level dynamics are generally unknown, although important given that adaptation and acclimation ...
Chang Jae Choi   +17 more
doaj   +1 more source

An Exploratory Study of Telomere Length in the Deep-Sea Shark, Etmopterus granulosus

open access: yesFrontiers in Marine Science, 2021
The history of elasmobranch ageing highlights the difficulty of age estimation in animals lacking ossified structures. Ageing techniques are numerous, yet all are limited by difficulties of validation and verification and inherent subjectivity.
Melissa C. Nehmens   +5 more
doaj   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

open access: yesAdvanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian   +5 more
wiley   +1 more source

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