Elagolix treatment in women with heavy menstrual bleeding associated with uterine fibroid: a systematic review and meta-analysis [PDF]
Background: Elagolix is effective and safe for treating menorrhagia in women with uterine fibroid. However, it is reported to be associated with hypoestrogenism that can be alleviated by adding estradiol/norethindrone acetate. This systematic review and
Ahmad, Imran+3 more
core +2 more sources
“Conceiving” the pill : the 45th birthday of the oral contraceptive pill in Europe [PDF]
In 1961, the first combined oral contraceptive pill was introduced in Europe. This pill contained ethinylestradiol (0.05mg) and northisterone (4mg). Nowadays, monophasic pill preparations contain a low dose (2035 g) of ethinylestradiol in combination ...
Brincat, Mark P., Calleja-Agius, Jean
core
Surgery versus hormonal therapy for deep endometriosis : is it a choice of the physician? [PDF]
Deep endometriosis, occurring approximately in 1% of women of reproductive age, represents the most severe form of endometriosis. It causes severe pain in the vast majority of affected women and it can affect the bowel and the urinary tract.
D. Dridi+5 more
core +1 more source
Menstrual disturbances in perimenopausal women: What's best? [PDF]
It's best to start with nonsteroidal anti- inflammatory drugs (NSAIDs), which effectively reduce heavy menstrual bleeding (strength of recommendation [SOR]: B, systematic review of randomized clinical trials [RCTs]).
Chen, Edward C.+2 more
core
Oral contraceptive progestins and angiotensin-dependent control of the renal circulation in humans [PDF]
Oral contraceptive (OC) use is associated with increased intra-renal renin-angiotensin-aldosterone system (RAA System) activity and risk of nephropathy, though the contribution of progestins contained in the OC in the regulation of angiotensin-dependent ...
Ahmed, Sofia B.+3 more
core +1 more source
A RAPID STABILITY INDICATING HPLC-METHOD FOR DETERMINATION OF NORETHISTERONE ACETATE IN PLASMA, TABLETS AND IN A MIXTURE WITH OTHER STEROIDS [PDF]
Objectives: This study reports about a simple, rapid and accurate, routine-HPLC method for quantification of Norethisterone acetate (NA) in bulk powder, tablets and plasma.Methods: The chromatographic separation is carried out using isocratic binary ...
Abd El-hay, Soad+2 more
core +1 more source
Drug interactions between non-rifamycin antibiotics and hormonal contraception: a systematic review [PDF]
ObjectiveTo determine whether interactions between non-rifamycin antibiotics and hormonal contraceptives result in decreased effectiveness or increased toxicity of either therapy.Data sourcesWe searched MEDLINE, Embase, clinicaltrials.gov and Cochrane ...
Curtis, Kathryn M.+3 more
core +2 more sources
The effect of low-dose combined hormone therapy (oestradiol and norethindrone acetate) on serum C-reactive protein levels and life quality in natural menopause women [PDF]
Servin Gocer+3 more
openalex +1 more source
Actual contamination of the Danube and Sava Rivers at Belgrade (2013) [PDF]
This study was focussed on a comprehensive investigation on the state of pollution of the Danube and Sava Rivers in the region of Belgrade. Different complementary analytical approaches were employed covering both i) organic contaminants in the river ...
Antonijević, Milan D.+22 more
core +2 more sources
A stepped-care approach to symptomatic endometriosis management : A participatory research initiative [PDF]
Objective: To assess the proportion of patients with symptomatic endometriosis satisfied with their medical treatment 12 months after enrollment in a stepped-care management protocol. Design: Prospective, single-arm, self-controlled study.
A. Donati+9 more
core +1 more source