Results 41 to 50 of about 2,160,316 (283)

Probabilities in Statistical Mechanics [PDF]

open access: yes, 2017
This chapter deals with the question of how we should think of the probabilities introduced in statistical mechanics. It is usually said that these probabilities are introduced on the basis of our ignorance of the precise state of the system, or our incapacity to treat analytically the equations of motion in order to deliver a detailed account of the ...
openaire   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Limit theorems for nondegenerate U-statistics of continuous semimartingales

open access: yes, 2014
This paper presents the asymptotic theory for nondegenerate $U$-statistics of high frequency observations of continuous It\^{o} semimartingales. We prove uniform convergence in probability and show a functional stable central limit theorem for the ...
Podolskij, Mark   +2 more
core   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Characterizations of Pareto, Weibull and Power Function Distributions Based On Generalized Order Statistics [PDF]

open access: yes, 2016
Characterizations of probability distributions by different regression conditions on generalized order statistics has attracted the attention of many researchers.
Ahsanullah, M., Hamedani, Gholamhossein
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Hot Hands, Streaks and Coin-flips: Numerical Nonsense in the New York Times

open access: yes, 2015
The existence of "Hot Hands" and "Streaks" in sports and gambling is hotly debated, but there is no uncertainty about the recent batting-average of the New York Times: it is now two-for-two in mangling and misunderstanding elementary concepts in ...
Gusfield, Dan
core  

Optimal properties of some Bayesian inferences

open access: yes, 2007
Relative surprise regions are shown to minimize, among Bayesian credible regions, the prior probability of covering a false value from the prior. Such regions are also shown to be unbiased in the sense that the prior probability of covering a false value
Evans, M., Shakhatreh, M.
core   +2 more sources

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