Results 41 to 50 of about 13,789 (243)

Pharmacosimulation of delays and interruptions during administration of tirofiban: a systematic comparison between EU and US dosage regimens. [PDF]

, 2022
Tirofiban is a glycoproteine (GP) IIb/IIIa receptor antagonist, which inhibits platelet-platelet aggregation and is a potential adjunctive antithrombotic treatment in patients with acute coronary syndromes (ACS) or high-risk percutaneous coronary ...
Gurbel, Paul A, Heramvand, Nadia, Jung, Christian, Karathanos, Athanasios, Kelm, Malte, Masyuk, Maryna, Muessig, Johanna M, Nia, Amir M, Polzin, Amin, Tantry, Udaya S, Valgimigli, Marco   +10 more
core   +1 more source

Severe thrombocytopenia induced by tirofiban after percutaneous coronary intervention: a case report

Journal of Medical Case Reports, 2023
Background Tirofiban is a nonpeptide glycoprotein IIb/IIIa receptor antagonist used widely in patients subjected to percutaneous coronary intervention.
Ze-Mu Wang, Bin Wang, Ya-Fei Li, Bei Chen, Qin Shen, Dian-Fu Li, Lian-Sheng Wang   +6 more
semanticscholar   +1 more source

Platelet Function and Risk of Bleeding in Patients With Acute Coronary Syndrome Following Tirofiban Infusion

Frontiers in Pharmacology, 2019
Aim: To assess platelet (PLT) function and bleeding risks in patients with acute coronary syndrome after tirofiban infusion.Methods: Patients diagnosed with acute coronary syndrome from May 2016 to February 2018 in the Department of Cardiac Intensive ...
Xiaoye Li, Shuning Zhang, Zi Wang, Qiuyi Ji, Qibing Wang, Xiaoyu Li, Qianzhou Lv   +6 more
doaj   +1 more source

A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins [PDF]

, 2017
Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation.
Cavalcanti-Adam, Elisabetta Ada, Geiger, Benjamin, Kapp, Tobias G., Kessler, Horst, Maltsev, Oleg V., Mas Moruno, Carlos, Neubauer, Stefanie, Notni, Johannes, Rechenmacher, Florian, Reuning, Ute, Spatz, Joachim, Wester, Hans-Jürgen, Zarka, Revital   +12 more
core   +2 more sources

Efficacy and safety of tirofiban injection with intracranial stenting in early reocclusion due to intracranial atherosclerosis

Interdisciplinary Neurosurgery, 2022
Objective: We aimed to develop an optimal protocol for failed mechanical thrombectomy (MT) in cases of emergent large vessel occlusion (ELVO) with intracranial atherosclerosis (ICAS).
Yun Ho Noh, Ji Young Lee, Seok Mann Yoon, Yu Jin Ha, Jaewoo Chung, Jung Ho Ko, Dong Seong Shin, Jae-Min Ahn, Hyuk Jin Oh, Jai-Joon Shim, Man Ryul Lee, Jae Sang Oh   +11 more
doaj  

Rescue Treatment with Intra-arterial Tirofiban Infusion and Emergent Carotid Stenting [PDF]

, 2008
Rapid arterial rethrombosis is associated with high-grade residual stenosis and usually occurs at the site of the initial occlusion, resulting in reocclusion of the recanalized artery.
Alexandrov, Dong Joon Kim, Heo, Ho, Kee Oog Lee, Kyung-Yul Lee, Lee, Liebeskind, Qureshi, Rukshin, Seitz, Straub, Tae Jin Song, The EPIC Investigators, Wallace   +14 more
core   +2 more sources

There is no difference in safety and efficacy with Tirofiban or Eptifibatide for patients undergoing treatment of large vessel occlusion and underlying intracranial atherosclerosis [PDF]

, 2021
Background Glycoprotein IIb/IIIa inhibitor use in acute ischemic stroke (AIS) during mechanical thrombectomy (MT) and acute stenting and angioplasty is a topic consistently debated due to concerns over safety and efficacy. Tirofiban is a glycoprotein IIb/
Georgiadis, Alexandros, Hassan, Ameer E., Kotta, Hari, Movva, Hari, Preston, Laurie, Rabah, Rani, Tekle, Wondwossen G.   +6 more
core   +1 more source

Safety and efficacy of different tirofiban administration routes on acute ischemic stroke patients with successful recanalization: A propensity score matching analysis

CNS Neuroscience & Therapeutics, 2022
This study aimed to explore the effect of different administration routes of a low dose of tirofiban on acute ischemic stroke (AIS) patients with successful recanalization after endovascular treatment (EVT).
Wenting Guo, Jiali Xu, Linqing Ma, Jin Ma, Sijie Li, Changhong Ren, Longfei Wu, Chuanjie Wu, Chuanhui Li, Jian Chen, J. Duan, Qingfeng Ma, Haiqing Song, Wenbo Zhao, X. Ji   +14 more
semanticscholar   +1 more source

Long-Term Outcomes of Local Tirofiban Infusion for Intracranial Atherosclerosis-Related Occlusion

Brain Sciences, 2022
Local tirofiban infusion has been reported as a rescue strategy for intracranial atherosclerotic stenosis (ICAS)-related stroke. However, the long-term outcomes of local tirofiban infusion during endovascular reperfusion therapy (ERT) for ICAS-related ...
Woochan Choi, Yang-Ha Hwang, Yong-Won Kim   +2 more
doaj   +1 more source

Prospective pilot study of tirofiban in progressive stroke after intravenous thrombolysis

Frontiers in Neurology, 2022
Background Intravenous thrombolysis (IVT) is a standard procedure for the treatment of patients with acute ischemic stroke (AIS). Improving the therapeutic efficacy of IVT is an important task for neurologists.
Yan Zhang, Jianliang Wang, Zhaoxi Ma, Guihua Mu, Dagan Liang, Yifan Li, Xiao Qian, Lu-Feng Zhang, F. Shen, Lei Zhang, Jie Yu, Yang Liu   +11 more
semanticscholar   +1 more source