Results 1 to 10 of about 24,814 (247)

Amitriptyline and Imipramine [PDF]

British Journal of Psychiatry, 1964
John M. Hoenig
openalex   +4 more sources

The half‐life of amitriptyline. [PDF]

British Journal of Clinical Pharmacology, 1978
HJ Rogers, PJ Morrison, ID Bradbrook
openalex   +5 more sources

Fullerene (C20) as a potential sensor for thermal and electrochemical detection of amitriptyline: A DFT study [PDF]

Journal of Chemistry Letters, 2020
In this research, amitriptyline adsorption on the surface of fullerene C20 was studied by density functional theory computations. The calculated adsorption energies showed amitriptyline interaction with C20 is experimentally possible. The negative values
Mohammad Reza Jalali Sarvestani, Zohreh Doroudi   +1 more
doaj   +1 more source

Low-dose titrated amitriptyline as second-line treatment for adults with irritable bowel syndrome in primary care: the ATLANTIS RCT

Health Technology Assessment
Background Irritable bowel syndrome, characterised by abdominal pain and a change in stool form or frequency, is most often managed in primary care. When first-line therapies are ineffective, National Institute for Health and Care Excellence guidelines ...
Alexandra Wright-Hughes, Alexander C Ford, Sarah L Alderson, Pei Loo Ow, Matthew J Ridd, Robbie Foy, Felicity L Bishop, Matthew Chaddock, Heather Cook, Deborah Cooper, Catherine Fernandez, Elspeth A Guthrie, Suzanne Hartley, Amy Herbert, Daniel Howdon, Delia P Muir, Sonia Newman, Christopher A Taylor, Emma J Teasdale, Ruth Thornton, Hazel A Everitt, Amanda J Farrin   +21 more
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Effect of amitriptyline on orthodontic tooth movement in rats: an experimental study [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects, 2020
Background. Orthodontic tooth movement (OTM) occurs in the alveolar bone; therefore, any condition affecting bone quality can alter OTM. This study aimed to evaluate the effect of amitriptyline on OTM in rats. Methods.
Mohammad Sadegh Ahmad Akhoundi, Mahdiyeh Shaygan-Mehr, Mohammad Ali Keshvad, Shahroo Etemad Moghaddam, Mojgan Alaeddini, Ahmadreza Dehpour, Amir Hossein Mirhashemi   +6 more
doaj   +1 more source

Amitriptyline inhibits the MAPK/ERK and CREB pathways and proinflammatory cytokines through A3AR activation in rat neuropathic pain models [PDF]

Korean Journal of Anesthesiology, 2019
Background The pain-relief properties of tricyclic antidepressants can be attributed to several actions. Recent observations suggest that adenosine is involved in the antinociceptive effect of amitriptyline.
Yumi Kim, So Young Kwon, Hong Soo Jung, Yoo Jung Park, Yong Shin Kim, Jang Hyeok In, Jin Woo Choi, Jin A Kim, Jin Deok Joo   +8 more
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Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients

Frontiers in Pharmacology, 2021
The tricyclic antidepressant amitriptyline is frequently prescribed but its use is limited by its narrow therapeutic range and large variation in pharmacokinetics.
Johannes Matthaei, Jürgen Brockmöller, Werner Steimer, Konstanze Pischa, Stefan Leucht, Maria Kullmann, Ole Jensen, Typhaine Ouethy, Mladen Vassilev Tzvetkov, Mladen Vassilev Tzvetkov, Muhammad Rafehi   +10 more
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Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways

Respiratory Research, 2023
Introduction The standard therapy for bronchial asthma consists of combinations of acute (short-acting ß2-sympathomimetics) and, depending on the severity of disease, additional long-term treatment (including inhaled glucocorticoids, long-acting ß2 ...
Paulina Hempel, Virag Klein, Anna Michely, Svenja Böll, Annette D. Rieg, Jan Spillner, Till Braunschweig, Saskia von Stillfried, Norbert Wagner, Christian Martin, Klaus Tenbrock, Eva Verjans   +11 more
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Percutaneous electrical nerve field stimulation compared to standard medical therapy in adolescents with functional abdominal pain disorders

Frontiers in Pain Research, 2023
IntroductionStandard medical therapy (SMT) in children with functional abdominal pain disorders (FAPD) includes cyproheptadine and amitriptyline. While percutaneous electrical nerve field stimulation (PENFS) has shown benefit, no study has compared ...
Neha R. Santucci, Neha R. Santucci, Rashmi Sahay, Khalil I. El-Chammas, Khalil I. El-Chammas, Kahleb Graham, Kahleb Graham, Mikaela Wheatley, Mikaela Wheatley, Madeleine Vandenbrink, Jennifer Hardy, Lin Fei   +11 more
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Acetylcholine Esterase Gene Expression in Salivary Glands of Albino Rats after Treatment with amitriptyline or/and Ashwagandha

Journal of Applied Veterinary Sciences, 2023
Acetylcholinesterase is required as an enzyme to counteract the effects of acetylcholine. The aim of the study is to assess how amitriptyline and Ashwagandha affect the acetylcholinesterase gene in rat salivary glands.
Ismail R. Idrees , Ghada A. Taqa , Saba Kh. A. Ibrahim   +2 more
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