Results 1 to 10 of about 11,347,707 (376)
A General Introduction to Glucocorticoid Biology [PDF]
Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation, autoimmune diseases, and cancer. To exert their broad physiological and therapeutic effects, GCs bind to the GC receptor (GR) which belongs to the nuclear receptor ...
Steven Timmermans+5 more
doaj +9 more sources
Development of an Online General Biology Open Educational Resource (OER) Laboratory Manual [PDF]
Currently, many academic institutions are using one or more variations of online modalities due to the COVID-19 pandemic, and science educators face a unique challenge with distance-learning laboratories.
Dmitry Y. Brogun+3 more
doaj +3 more sources
A general theory for temperature-dependence in biology [PDF]
AbstractAt present, there is no simple, complete, and first principles-based model for quantitatively describing the full range of observed biological temperature responses. Here, we derive a theory exhibiting these features based on the Eyring-Evans-Polanyi theory governing chemical reaction rates, and which is applicable across all scales from the ...
José Ignacio Arroyo+4 more
semanticscholar +6 more sources
A general protocol for the generation of Nanobodies for structural biology [PDF]
There is growing interest in using antibodies as auxiliary tools to crystallize proteins. Here we describe a general protocol for the generation of Nanobodies to be used as crystallization chaperones for the structural investigation of diverse conformational states of flexible (membrane) proteins and complexes thereof.
Els Pardon+9 more
semanticscholar +8 more sources
THE COURSE IN GENERAL BIOLOGY [PDF]
n ...
John M. Coulter
openalex +5 more sources
Borges Dilemma, Fundamental Laws, and Systems Biology [PDF]
I reason here that the known folk law in biology that there is no general law in biology because of exceptions is false. The (quantitative) systems biology offers the potential to solve the Borges Dilemma, by transcending it. There have already a plenty of indications on this trend.
Ao, P
arxiv +5 more sources
Biology, General and Medical [PDF]
Includes index. ; Includes bibliographical references. ; Mode of access: Internet.
A. D.
openalex +2 more sources
A family tree of Markov models in systems biology [PDF]
Motivated by applications in systems biology, we seek a probabilistic framework based on Markov processes to represent intracellular processes. We review the formal relationships between different stochastic models referred to in the systems biology literature. As part of this review, we present a novel derivation of the differential Chapman-Kolmogorov
Alfonsi+33 more
arxiv +3 more sources
Chemoreception in the context of the general biology of ROS [PDF]
Superoxide anion is the most important reactive oxygen species (ROS) primarily generated in cells. The main cellular constituents with capabilities to generate superoxide anion are NADPH oxidases and mitochondrial respiratory chain. The emphasis of our article is centered in critically examining hypotheses proposing that ROS generated by NADPH oxidase ...
C. González+8 more
openalex +5 more sources