Results 1 to 10 of about 21,195 (193)

Different keratoconus definitions can lead to substantial prevalence disparities in population-based studies. [PDF]

Sci Rep
This report explores the prevalence of keratoconus in a population-based cohort of adults aged 40 or older according to ten different definitions. All Rotterdam Study participants with reliable Pentacam scans and no prior corneal refractive surgery were ...
Shabani H, van Dooren BTH, Meester-Smoor MA, Geerards AAJM, Klaver CCW, Ramdas WD.   +5 more
europepmc   +2 more sources

Comprehensive genetic screening for vascular Ehlers–Danlos syndrome through an amplification‐based next‐generation sequencing system

American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 37-51, January 2023., 2023
Abstract Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder (HCTD) characterized by arterial dissection/aneurysm/rupture, sigmoid colon rupture, or uterine rupture. Diagnosis is confirmed by detecting heterozygous variants in COL3A1.
Tomomi Yamaguchi, Shujiro Hayashi, Daisuke Hayashi, Takeshi Matsuyama, Norimichi Koitabashi, Kenichi Ogiwara, Masaaki Noda, Chiai Nakada, Shinya Fujiki, Akira Furutachi, Yasuhiko Tanabe, Michiko Yamanaka, Aki Ishikawa, Miyako Mizukami, Asako Mizuguchi, Kazumitsu Sugiura, Makoto Sumi, Hirokuni Yamazawa, Atsushi Izawa, Yuko Wada, Tomomi Fujikawa, Yuri Takiguchi, Keiko Wakui, Kyoko Takano, Shin‐Ya Nishio, Tomoki Kosho   +25 more
wiley   +1 more source

New Keratoconus Risk Factors: A Cross-Sectional Case—Control Study

Journal of Ophthalmology, 2022
Purpose. To evaluate risk factors associated with keratoconus in a monocentric cross-sectional case-control study. Methods. This observational study occurred from June 2019 to February 2021 in a university hospital (France).
Eloi Debourdeau, Gabriel Planells, Chloe Chamard, David Touboul, Max Villain, Pascal Demoly, Fanny Babeau, Pierre Fournie, Vincent Daien   +8 more
doaj   +1 more source

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

Contrast sensitivity and higher-order aberrations in Keratoconus subjects

Scientific Reports, 2021
This study analyzes the relationship between contrast-sensitivity and higher-order aberrations (HOA) in mild and subclinical-keratoconus in subjects with good visual-acuity (VA).
Einat Shneor, David P. Piñero, Ravid Doron   +2 more
doaj   +1 more source

Theranostic‐guided corneal cross‐linking: Preclinical evidence on a new treatment paradigm for keratoconus

Journal of Biophotonics, Volume 15, Issue 12, December 2022., 2022
Theranostics is an emerging therapeutic paradigm of personalized and precision medicine that performs therapy guided by molecular diagnostic imaging. The technology was implemented in a UV‐A medical device and showed to efficiently drive the operator in performing personalized riboflavin/UV‐A corneal cross‐linking for treatment of corneal disorders ...
Giuseppe Lombardo, Giuseppe Massimo Bernava, Sebastiano Serrao, Marco Lombardo   +3 more
wiley   +1 more source

Anterior segment characteristics in normal and keratoconus eyes evaluated with a new type of swept-source optical coherence tomography.

PLoS ONE, 2022
PurposeThis study aimed to evaluate and compare the discriminating ability of corneal elevation maps generated using a swept-source optical coherence tomography (SS-OCT) (SS-OCT ANTERION, Heidelberg Engineering, Heidelberg, Germany), which was estimated ...
Kook Young Kim, Seongjun Lee, Young Joon Jeon, Ji Sang Min   +3 more
doaj   +1 more source

The correlation between keratoconus and eye rubbing: a review [PDF]

International Journal of Ophthalmology, 2019
Keratoconus is a non-inflammatory disorder which is gradual in development; corneal thinning and ectatic protrusion characterizes it. Keratoconus prevalence varies between different regions depending on several factors that affecting its prevalence ...
Hatim Najmi, Yara Mobarki, Khalid Mania, Bashaer Altowairqi, Mohammed Basehi, Mohammed Salih Mahfouz, Mona Elmahdy   +6 more
doaj   +1 more source

In-vivo corneal biomechanical analysis of unilateral keratoconus [PDF]

International Journal of Ophthalmology, 2015
AIM: To evaluate and compare corneal biomechanical findings measured by ocular response analyzer, topographic and pachymetric findings in patients with unilateral keratoconus patients and healthy controls. METHODS: This is an observational, case-control
Orhan Ayar, Mehmet Cuneyt Ozmen, Orkun Muftuoglu, Mehmet Orcun Akdemir, Mustafa Koc, Kemal Ozulken   +5 more
doaj   +1 more source

Quantitative comparison of corneal surface areas in keratoconus and normal eyes

Scientific Reports, 2021
Keratoconus is a highly prevalent corneal disorder characterized by progressive corneal thinning, steepening and irregular astigmatism. To date, pathophysiology of keratoconus development and progression remains debated. In this study, we retrospectively
François-Xavier Crahay, Guillaume Debellemanière, Stephan Tobalem, Wassim Ghazal, Sarah Moran, Damien Gatinel   +5 more
doaj   +1 more source