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Kidney diseases

open access: yesImmunological Reviews, 2022
SummaryDysregulation and accelerated activation of the alternative pathway (AP) of complement is known to cause or accentuate several pathologic conditions in which kidney injury leads to the appearance of hematuria and proteinuria and ultimately to the development of chronic renal failure.
Erica Daina   +2 more
openaire   +2 more sources

Postbiotics and Kidney Disease

open access: yesToxins, 2022
Chronic kidney disease (CKD) is projected to become the fifth global cause of death by 2040 as a result of key shortcomings in the current methods available to diagnose and treat kidney diseases. In this regard, the novel holobiont concept, used to describe an individual host and its microbial community, may pave the way towards a better understanding ...
Chiara Favero   +5 more
openaire   +6 more sources

Kidney age, not kidney disease [PDF]

open access: yesCanadian Medical Association Journal, 2018
KEY POINTS Although a variety of conditions and syndromes may affect the kidneys over either chronic or acute time frames, the term “chronic kidney disease” (CKD) is used to describe a decrease in the filtration ability of the glomerular capillaries in the kidney.
Stevens, Richard J   +10 more
openaire   +7 more sources

CD74 in Kidney Disease [PDF]

open access: yesFrontiers in Immunology, 2015
CD74 (invariant MHC class II) regulates protein trafficking and is a receptor for macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT/MIF-2). CD74 expression is increased in tubular cells and/or glomerular podocytes and parietal cells in human metabolic nephropathies, polycystic kidney disease, graft rejection and kidney ...
Lara eValiño-Rivas   +7 more
openaire   +5 more sources

Probiotics for kidney disease

open access: yesClinical Kidney Journal, 2022
ABSTRACT Diet has long been known to influence the course of chronic kidney disease (CKD) and may even result in acute kidney injury (AKI). Diet may influence kidney disease through a direct impact of specific nutrients on the human body through modulation of the gut microbiota composition or through metabolites generated by the gut ...
Favero, Chiara   +2 more
openaire   +3 more sources

COMPARISON OF SUCCESSFUL OUTCOME OF FLAP VERSUS NO-FLAP IN O’CONOR & SOKOL TECHNIQUE FOR VESICOVAGINAL FISTULA REPAIR

open access: yesKhyber Medical University Journal, 2020
OBJECTIVE: To compare the successful outcome of flap versus no-flap in O’Conor & Sokol technique for simple vesicovaginal fistula (VVF) repair. METHODS: This quasi-experimental study was conducted in department of Urology, Institute of Kidney Diseases,
Liaqat Ali   +5 more
doaj   +1 more source

miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies

open access: yesStem Cell Research & Therapy, 2019
Stem cell therapy has been applied in many fields. Basic and clinical studies on stem cell therapy for acute kidney injury (AKI) have been conducted. Stem cells have been found to exert renal protection through a variety of mechanisms, such as regulating
Si-Yang Wang   +5 more
doaj   +1 more source

Kidney: polycystic kidney disease [PDF]

open access: yesWIREs Developmental Biology, 2014
Polycystic kidney disease (PKD) is a life‐threatening genetic disorder characterized by the presence of fluid‐filled cysts primarily in the kidneys. PKD can be inherited as autosomal recessive (ARPKD) or autosomal dominant (ADPKD) traits. Mutations in either the PKD1 or PKD2 genes, which encode polycystin 1 and polycystin 2, are the underlying cause of
Gregory B. Vanden Heuvel   +2 more
openaire   +3 more sources

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