Results 1 to 10 of about 1,851,786 (318)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Real-time optoacoustic temperature determination on cell cultures during heat exposure: a feasibility study

International Journal of Hyperthermia, 2019
Objective/Purpose: In order to study the effects of hyperthermia and other temperature-related effects on cells and tissues, determining the precise time/temperature course is crucial.
Yoko Miura, Eric Seifert, Josua Rehra, Katharina Kern, Dirk Theisen-Kunde, Michael Denton, Ralf Brinkmann   +6 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Magnetized fast isochoric laser heating for efficient creation of ultra-high-energy-density states

Nature Communications, 2018
It is desirable to deposit more energy in the dense plasma core to trigger the fusion ignition. Here the authors demonstrate enhanced energy coupling from laser to plasma core by using solid targets and guiding the transport of relativistic electron beam
Shohei Sakata, Seungho Lee, Hiroki Morita, Tomoyuki Johzaki, Hiroshi Sawada, Yuki Iwasa, Kazuki Matsuo, King Fai Farley Law, Akira Yao, Masayasu Hata, Atsushi Sunahara, Sadaoki Kojima, Yuki Abe, Hidetaka Kishimoto, Aneez Syuhada, Takashi Shiroto, Alessio Morace, Akifumi Yogo, Natsumi Iwata, Mitsuo Nakai, Hitoshi Sakagami, Tetsuo Ozaki, Kohei Yamanoi, Takayoshi Norimatsu, Yoshiki Nakata, Shigeki Tokita, Noriaki Miyanaga, Junji Kawanaka, Hiroyuki Shiraga, Kunioki Mima, Hiroaki Nishimura, Mathieu Bailly-Grandvaux, João Jorge Santos, Hideo Nagatomo, Hiroshi Azechi, Ryosuke Kodama, Yasunobu Arikawa, Yasuhiko Sentoku, Shinsuke Fujioka   +38 more
doaj   +1 more source

Optical Fiber Amplifiers: Optimization and PerformanceEvaluation

Diyala Journal of Engineering Sciences, 2019
This work demonstrates the simulation of two different types of optical fiber amplifiers (OFA) utilizing OptiSystem–10, namely, 3 m length of erbium doped fiber amplifier (EDFA) and 7 km length of Raman fiber amplifier (RFA).
A. k. Abass, Mohammed J. Abdul-Razak, Haneen H. Mohammed, Suad M. Kadhim, Mohammed A. Salih   +4 more
doaj   +1 more source

Engineering nanoparticle features to tune Rayleigh scattering in nanoparticles-doped optical fibers

Scientific Reports, 2021
Rayleigh scattering enhanced nanoparticles-doped optical fibers are highly promising for distributed sensing applications, however, the high optical losses induced by that scattering enhancement restrict considerably their sensing distance to few meters.
Victor Fuertes, Nicolas Grégoire, Philippe Labranche, Stéphane Gagnon, Ruohui Wang, Yannick Ledemi, Sophie LaRochelle, Younès Messaddeq   +7 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Forage characteristics of Vicia sativa L. and Trifolium resupinatum L. in catch crop systems under Central European conditions

Plant, Soil and Environment, 2005
In a field experiment the development of dry matter yield and forage quality of the catch crop Vicia sativa L. compared with Trifolium resupinatum L. was investigated and the suitability for cultivation in a mixture with Lolium multiflorum ssp. gaudinii (
W. Opitz Von Boberfeld, E. Beckmann, H. Laser   +2 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source