Association between early ondansetron use and the risk of sepsis in intensive care unit patients: a secondary data of the Medical Information Mart for Intensive Care IV database [PDF]
BMJ OpenObjective This study planned to analyse the association between ondansetron use within 24 hours before intensive care unit (ICU) admission to within 48 hours after ICU admission and the risk of sepsis in ICU patients.Design A cohort study.Setting and ...
Xuan Liu, Qiuye Kou, Enhe Liu
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Comparison of aprepitant versus ondansetron for prevention of postoperative nausea and vomiting: A systematic review and meta-analysis with trial sequential analysis [PDF]
Indian Journal of AnaesthesiaBackground and Aims: Postoperative nausea and vomiting (PONV) is a common complication after surgery. Preventing PONV in high-risk patients often requires a multimodal approach combining antiemetic drugs with diverse mechanisms.
Madhusudan P. Singh +3 more
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The therapeutic targets and signaling mechanisms of ondansetron in the treatment of critical illness in the ICU [PDF]
Frontiers in PharmacologyBackgroundThere is accumulating evidence regarding the benefits of the 5-HT3 receptor antagonist ondansetron for the treatment of critical illness due to its potential anti-inflammatory effect.
Lili Tao +5 more
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The effect of ondansetron and K-K9 Acupressure with ondansetron in treatment of nausea and vomiting of pregnancy [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2021 Introduction: Nausea and vomiting in pregnancy is one of the most common problems during pregnancy. Given that there is no research on the use of a combination method of acupressure and antiemetic drugs in reducing nausea and vomiting in pregnancy ...
Shohreh Kheiri Gharibvand +3 more
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Inhibition of Small-Conductance, Ca2+-Activated K+ Current by Ondansetron
Frontiers in Pharmacology, 2021 Background: Small-conductance Ca2+-activated K+ channels (SK channels) have been proposed as antiarrhythmic targets for the treatment of atrial fibrillation.
Shuai Guo +4 more
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Ondansetron and seizures [PDF]
Epilepsia, 2009 SummaryExperimental studies suggest that 5‐hydroxytryptamine (5‐HT) receptors play a role in epileptogenesis and seizure propagation. Ondansetron, a 5‐HT3receptor antagonist, has been reported to have proconvulsant and anticonvulsant effects in animals. We describe three patients who developed seizures after receiving ondansetron.
Jayant N. Acharya +4 more
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Clinical and Translational Science, 2023 Administration of a widely used 5‐hydroxytryptamine receptor (5HT3AR) antagonist (ondansetron) potently inhibited the development of experimentally induced opioid dependence and withdrawal responses in mice and humans.
Manhong Wu +4 more
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Comparison of the Effects of Ondansetron and Ginger on Nausea and Vomiting in Pregnancy: A Clinical Trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2023 Introduction: Nausea and vomiting are the most common complications of pregnancy. In order to minimize the consumption of chemical drugs and prevent their side effects in pregnant women, this study was conducted with aim to compare the effect of ...
Mitra Tadayon najafabadi +3 more
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Extrapyramidal reaction to ondansetron [PDF]
Cancer, 1992 AbstractThe authors present a case report and discussion of a patient who experienced an unusual untoward extrapyramidal reaction to ondansetron, a 5HT3‐antiseratonin receptor blocking agent used to treat chemotherapy‐induced vomiting.
Barbara Murphy, Joseph R. Halperin
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Changes in intravenous hydration frequency and emergency department length of stay after implementation of oral ondansetron therapy in children with dehydration due to acute gastroenteritis [PDF]
Pediatric Emergency Medicine Journal, 2018 Purpose Oral ondansetron is a safe and effective antiemetic drug to facilitate oral rehydration therapy in acute gastroenteritis (AGE) with mild dehydration.
Soon Kwang Kwon +5 more
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