Results 1 to 10 of about 1,120,757 (338)

Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development

Nature Communications, 2022
Possible distinct contributions of Runx 2 and Runx3 in osteoarthritis have not been clarified. Nagata et al. show that Runx3 protects adult articular cartilage by extracellular matrix protein production in normal conditions, while Runx2 exerts both ...
Kosei Nagata, Hironori Hojo, Song Ho Chang, Hiroyuki Okada, Fumiko Yano, Ryota Chijimatsu, Yasunori Omata, Daisuke Mori, Yuma Makii, Manabu Kawata, Taizo Kaneko, Yasuhide Iwanaga, Hideki Nakamoto, Yuji Maenohara, Naohiro Tachibana, Hisatoshi Ishikura, Junya Higuchi, Yuki Taniguchi, Shinsuke Ohba, Ung-il Chung, Sakae Tanaka, Taku Saito   +21 more
doaj   +1 more source

Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human

Stem Cell Research & Therapy, 2021
Background Somatic stem cell transplantation has been performed for cartilage injury, but the reparative mechanisms are still conflicting. The chondrogenic potential of stem cells are thought as promising features for cartilage therapy; however, the ...
Chijimatsu Ryota, Miwa Satoshi, Okamura Gensuke, Miyahara Junya, Tachibana Naohiro, Ishikura Hisatoshi, Higuchi Junya, Maenohara Yuji, Tsuji Shinsaku, Sameshima Shin, Takagi Kentaro, Nakazato Keiu, Kawaguchi Kohei, Yamagami Ryota, Inui Hiroshi, Taketomi Shuji, Sakae Tanaka, Taku Saito   +17 more
doaj   +1 more source

Characteristics of three-dimensional acetabular morphology of patients with excellent outcome after rotational acetabular osteotomy over 20 years

Journal of Orthopaedic Surgery and Research, 2021
Background Rotational acetabular osteotomy (RAO) is a type of pelvic osteotomy performed to improve the acetabular bony coverage against the femoral head for patients with acetabular dysplasia.
Takeyuki Tanaka, Toru Moro, Hisatoshi Ishikura, Kazuaki Hashikura, Taizo Kaneko, Sakae Tanaka   +5 more
doaj   +1 more source

Implementation of relative phase analysis to evaluate continuous interlimb coordination and stability in individuals with lower limb loss: Design and protocol for a retrospective analysis

BMJ Open, 2023
Introduction The number of people with lower limb loss continues to grow, though most research to date has been non-committal and lacks the appropriate clinical guidance required for proper prosthetic prescription.
Alexis N Sidiropoulos, Jason T Maikos, David V Herlihy   +2 more
doaj   +1 more source

Failure of preventive treatments in migraine: an observational retrospective study in a tertiary headache center

BMC Neurology, 2020
Background Although the criteria for acute migraine treatment and prevention have been well described, there are still unmet needs, general underuse and low benefits of preventive drugs.
Marianna Delussi, Eleonora Vecchio, Giuseppe Libro, Silvia Quitadamo, Marina de Tommaso   +4 more
doaj   +1 more source

Pathomechanism of intervertebral disc degeneration

JOR Spine, 2020
Intervertebral disc degeneration (IDD) is the main contributor to low back pain, which is a leading cause of disability worldwide. Although substantial progress has been made in elucidating the molecular mechanisms of IDD, fundamental and long‐lasting ...
Takeshi Oichi, Yuki Taniguchi, Yasushi Oshima, Sakae Tanaka, Taku Saito   +4 more
doaj   +1 more source

Neuroanatomy of the Cetacean Sensory Systems

Animals, 2023
Cetaceans have undergone profound sensory adaptations in response to their aquatic environment during evolution. These adaptations are characterised by anatomo-functional changes in the classically defined sensory systems, shaping their neuroanatomy accordingly.
Steffen De Vreese, Ksenia Orekhova, Maria Morell, Tommaso Gerussi, Jean-Marie Graïc   +4 more
openaire   +5 more sources

Easily-Deployable Acoustic Local Positioning System Based on Auto-Calibrated Wireless Beacons

Sensors, 2019
Self-calibrated Acoustic Local Positioning Systems (ALPS) generally require a high consumption of hardware and software resources to obtain the user’s position at an acceptable update rate.
José A. Moreno, Fernando J. Álvarez, Teodoro Aguilera, José A. Paredes   +3 more
doaj   +1 more source

Heatwave-Like Events During Development Are Sufficient to Impair Bumblebee Worker Responses to Sensory Stimuli

Frontiers in Ecology and Evolution, 2022
Heatwaves are increasingly common globally and are known to have detrimental impacts on animal morphology and behaviour. These impacts can be severe, especially if heatwaves occur during development, even on animals that can regulate the temperature of ...
Craig D. Perl, Craig D. Perl, Zanna B. Johansen, Zahra Moradinour, Marie Guiraud, C. E. Restrepo, Vun Wen Jie, A. Miettinen, A. Miettinen, Emily Baird, Emily Baird   +10 more
doaj   +1 more source

Roboethics in Remote Human Interactions and Rehabilitative Therapeutics

Applied Sciences, 2022
Global aging, the need for continuous high-quality services, and the recent COVID-19 pandemic have caused many sectors to reduce in-person contact between individuals where possible, and to instead use remote communication technology.
Ali Maddahi, Tracy R. Leach, Mohammad Saeedi, Pruthvinath R. Dhannapuneni, Yaser Maddahi, Mohamed-Amine Choukou, Kourosh Zareinia   +6 more
doaj   +1 more source