Results 1 to 10 of about 337,689 (296)

Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells

eLife, 2022
Acute myeloid leukaemia (AML) cells interact and modulate components of their surrounding microenvironment into their own benefit. Stromal cells have been shown to support AML survival and progression through various mechanisms.
Nuria Vilaplana-Lopera, Vincent Cuminetti, Ruba Almaghrabi, Grigorios Papatzikas, Ashok Kumar Rout, Mark Jeeves, Elena González, Yara Alyahyawi, Alan Cunningham, Ayşegül Erdem, Frank Schnütgen, Manoj Raghavan, Sandeep Potluri, Jean-Baptiste Cazier, Jan Jacob Schuringa, Michelle AC Reed, Lorena Arranz, Ulrich L Günther, Paloma Garcia   +18 more
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The Effect of Mesenchymal Stromal Cells Derived From Endometriotic Lesions on Natural Killer Cell Function

Frontiers in Cell and Developmental Biology, 2021
Endometriosis is an inflammatory disease that presents with ectopic endometriotic lesions. Reduced immunosurveillance of these lesions has been proposed to be playing a role in the pathology of endometriosis.
Fawaz Abomaray, Arnika Kathleen Wagner, Michael Chrobok, Åsa Ekblad-Nordberg, Sebastian Gidlöf, Sebastian Gidlöf, Evren Alici, Cecilia Götherström   +7 more
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Stromal cells in the tumor microenvironment: accomplices of tumor progression?

Cell Death and Disease, 2023
The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.
Yan Zhao, Meili Shen, Liangqiang Wu, Haiqin Yang, Yixuan Yao, Qingbiao Yang, Jianshi Du, Linlin Liu, Yapeng Li, Yuansong Bai   +9 more
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Spontaneous cancer-stromal cell fusion as a mechanism of prostate cancer androgen-independent progression. [PDF]

PLoS ONE, 2012
We have previously shown that human prostate cancer cells are capable of acquiring malignant attributes through interaction with stromal cells in the tumor microenvironment, while the interacting stromal cells can also become affected with both ...
Ruoxiang Wang, Xiaojuan Sun, Christopher Y Wang, Peizhen Hu, Chia-Yi Chu, Shurong Liu, Haiyen E Zhau, Leland W K Chung   +7 more
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Umbilical cord mesenchymal stromal cells—from bench to bedside

Frontiers in Cell and Developmental Biology, 2022
In recent years, mesenchymal stromal cells (MSCs) have generated a lot of attention due to their paracrine and immuno-modulatory properties. mesenchymal stromal cells derived from the umbilical cord (UC) are becoming increasingly recognized as having ...
Shashank Chetty, Reza Yarani, Reza Yarani, Ganesh Swaminathan, Rosita Primavera, Shobha Regmi, Sravanthi Rai, Jim Zhong, Abantika Ganguly, Avnesh S Thakor   +9 more
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Bone marrow mesenchymal stromal cell-derived small extracellular vesicles: A novel therapeutic agent in ischemic heart diseases

Frontiers in Pharmacology, 2023
Myocardial injury is a major pathological factor that causes death in patients with heart diseases. In recent years, mesenchymal stromal cells (MSCs) have been generally used in treating many diseases in animal models and clinical trials.
Wenguang Chang, Peifeng Li
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Lymph Node Stromal Cells From Different Draining Areas Distinctly Regulate the Development of Chronic Intestinal Inflammation

Frontiers in Immunology, 2021
The balance between the responsiveness of the intestinal immune system and the gut environment is fundamental for the maintenance of intestinal homeostasis, which is required for an adequate recognition of entering antigens.
Marijana Basic, Pia Pascale Peppermüller, Silvia Bolsega, André Bleich, Melanie Bornemann, Ulrike Bode, Manuela Buettner, Manuela Buettner   +7 more
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Can a Conversation Between Mesenchymal Stromal Cells and Macrophages Solve the Crisis in the Inflamed Intestine?

Frontiers in Pharmacology, 2018
Inflammatory bowel disease (IBD) is a group of chronic inflammatory conditions of the gastrointestinal tract characterized by an exacerbated mucosal immune response.
Laura Hidalgo-Garcia, Julio Galvez, M. Elena Rodriguez-Cabezas, Per O. Anderson   +3 more
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Mesenchymal stromal cell therapy for damaged retinal ganglion cells, is gold all that glitters?

Neural Regeneration Research, 2019
Mesenchymal stromal cells are an excellent source of stem cells because they are isolated from adult tissues or perinatal derivatives, avoiding the ethical concerns that encumber embryonic stem cells.
Fernando Lucas-Ruiz, Caridad Galindo-Romero, David García-Bernal, María Norte-Muñoz, Kristy T Rodríguez-Ramírez, Manuel Salinas-Navarro, Jose E Millán-Rivero, Manuel Vidal-Sanz, Marta Agudo-Barriuso   +8 more
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Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies

Frontiers in Cell and Developmental Biology, 2023
Introduction: The glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab has been licensed for treatment in follicular non-Hodgkin lymphoma and B-CLL following clinical trials demonstrating superior outcomes to standard of care treatment ...
Ester Fagnano, Swati Pendharkar, Madyson Colton, Philip N. Jones, Marta Crespi Sallan, Tetyana Klymenko, Andrejs Braun, Christian Klein, Jamie Honeychurch, Eleanor J. Cheadle, Timothy M. Illidge   +10 more
doaj   +1 more source