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Thyroid Hormones and Cancer: A Comprehensive Review of Preclinical and Clinical Studies
Thyroid hormones take major part in normal growth, development and metabolism. Over a century of research has supported a relationship between thyroid hormones and the pathophysiology of various cancer types.
Eilon Krashin+7 more
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Thyroid hormones in diabetes, cancer, and aging
Thyroid function is central in the control of physiological and pathophysiological processes. Studies in animal models and human research have determined that thyroid hormones modulate cellular processes relevant for aging and for the majority of age ...
Alejandro Martín-montalvo+2 more
exaly +2 more sources
Role of maternal thyroid hormones in the developing neocortex and during human evolution
The importance of thyroid hormones during brain development has been appreciated for many decades. In humans, low levels of circulating maternal thyroid hormones, e.g.
Denise eStenzel, Wieland B eHuttner
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Measurement of salivary thyroid hormones using the LC-MS/MS technique in a clinical setting [PDF]
Background: Saliva could be an attractive alternative to blood for assessing thyroid hormonal function. Objectives: Our goal was to determine if the levels of thyroid hormones in saliva can accurately reflect a person’s thyroid status and if they ...
Nadia Sawicka-Gutaj+10 more
doaj +2 more sources
Thyroid hormones in male reproduction and infertility
Thyroid hormones have been well studied for its relevance to male reproduction in the last few decades. They are considered as essential regulators of male reproductive functions and play vital roles in male gonadal developments.
Ahmed Alahmar+2 more
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Changes in Central Sensitivity to Thyroid Hormones vs. Urine Iodine during Pregnancy [PDF]
Introduction/Aim: Central sensitivity to thyroid hormones refers to the responsiveness of the hypothalamic–pituitary–thyroid (HPT) axis to changes in circulating free thyroxine (fT4).
Ioannis Ilias+8 more
doaj +2 more sources
Thyroid hormones and neurological impairments during the first two days after stroke: A pilot study [PDF]
Despite plenty of studies on the change in thyroid hormones after stroke, there is still no consensus for a comprehensive conclusion and clinical application.
Kobra Akhoundzadeh+3 more
doaj +2 more sources
Thyroid Hormone Transporters [PDF]
Thyroid hormone is essential for the development of the brain and the nervous system. Cellular entry is required for conversion of thyroid hormones by the intracellular deiodinases and for binding of T(3) to its nuclear receptors. Several transporters capable of thyroid hormone transport have been identified. Functional expression studies using Xenopus
Theo J. Visser+3 more
openaire +6 more sources
Endocrine Regulation on Bone by Thyroid
BackgroundAs an endocrine organ, the thyroid acts on the entire body by secreting a series of hormones, and bone is one of the main target organs of the thyroid.SummaryThis review highlights the roles of thyroid hormones and thyroid diseases in bone ...
Siyuan Zhu+7 more
doaj +1 more source
Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency
Background The monocarboxylate transporter 8 (MCT8) plays a vital role in maintaining brain thyroid hormone homeostasis. This transmembrane transporter is expressed at the brain barriers, as the blood–brain barrier (BBB), and in neural cells, being the ...
Marina Guillén-Yunta+6 more
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