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Poisoning with Thyroid Hormones Used Illegally—Systematic Review [PDF]

open access: yesPharmaceuticals
Background/Objectives: Thyroid hormones, considered safe in therapeutic doses, are used to treat hypothyroidism, a common condition. Due to a combination of factors, including their mechanism of action, availability, and low price, these drugs are used ...
Monika Skrzypiec-Spring   +7 more
doaj   +2 more sources

Can increased prenatal exposure to thyroid hormones alter physiology and behaviour in the long-term? Insights from an experimental study in Japanese quails [PDF]

open access: yesPeerJ
Maternal thyroid hormones (triiodothyronine T3 and thyroxine T4) are important regulators of embryonic development and gene expression. In chickens, prenatal thyroid hormone treatment has been shown to influence embryonic gene expression and postnatal ...
Kalle Aho   +4 more
doaj   +3 more sources

Thyroid Hormone Transporters [PDF]

open access: yesBiochemical Society Transactions, 2005
Thyroid hormone is essential for the development of the brain and the nervous system. Cellular entry is required for conversion of thyroid hormones by the intracellular deiodinases and for binding of T(3) to its nuclear receptors. Several transporters capable of thyroid hormone transport have been identified. Functional expression studies using Xenopus
Friesema, Edith   +3 more
  +8 more sources

Endocrine Regulation on Bone by Thyroid

open access: yesFrontiers in Endocrinology, 2022
BackgroundAs an endocrine organ, the thyroid acts on the entire body by secreting a series of hormones, and bone is one of the main target organs of the thyroid.SummaryThis review highlights the roles of thyroid hormones and thyroid diseases in bone ...
Siyuan Zhu   +7 more
doaj   +1 more source

Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency

open access: yesFluids and Barriers of the CNS, 2023
Background The monocarboxylate transporter 8 (MCT8) plays a vital role in maintaining brain thyroid hormone homeostasis. This transmembrane transporter is expressed at the brain barriers, as the blood–brain barrier (BBB), and in neural cells, being the ...
Marina Guillén-Yunta   +6 more
doaj   +1 more source

The potential usage of thyroid hormones as sport doping - a mini-review

open access: yesQuality in Sport, 2022
A thyroid gland is one of the most important organs of a human body. Thyroid hormones, at least in physiological concentration, have anabolic features.
Jakub Gałązka
doaj   +1 more source

Unveiling the nongenomic actions of thyroid hormones in adult mammalian brain: The legacy of Mary B. Dratman

open access: yesFrontiers in Endocrinology, 2023
A comprehensive review was conducted to compile the contributions of Mary B. Dratman and studies by other researchers in the field of nongenomic actions of thyroid hormones in adult mammalian brain.
Nilkanta Chakrabarti   +4 more
doaj   +1 more source

Analysis of free, unbound thyroid hormones by liquid chromatography‐tandem mass spectrometry: A mini‐review of the medical rationale and analytical methods

open access: yesAnalytical Science Advances, 2023
Measurement of hormones is important for the diagnosis and management of endocrine diseases. The thyroid hormones thyroxine (T4) and triiodothyronine (T3) are among the most commonly measured hormones in clinical laboratories, and it is the concentration
Alexander B. Westbye   +4 more
doaj   +1 more source

Comparison of Thyroid Hormone Levels Between Patients With Major Depressive Disorder and Healthy Individuals in China

open access: yesFrontiers in Psychiatry, 2021
Abnormal thyroid function in major depressive disorder (MDD) has been studied extensively, but the results still remain inconsistent. In China, few large-scale studies have investigated the differences in the levels of thyroid hormones between patients ...
Yanan Zhou   +11 more
doaj   +1 more source

Thyroid Hormone Transporters [PDF]

open access: yesEndocrine Reviews, 2019
AbstractThyroid hormone transporters at the plasma membrane govern intracellular bioavailability of thyroid hormone. Monocarboxylate transporter (MCT) 8 and MCT10, organic anion transporting polypeptide (OATP) 1C1, and SLC17A4 are currently known as transporters displaying the highest specificity toward thyroid hormones.
Stefan Groeneweg   +4 more
openaire   +3 more sources

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