Results 1 to 10 of about 3,224,961 (325)
Therapeutic Advances in Neurological Disorders, 2012 White matter dementia (WMD) is a syndrome introduced in 1988 to highlight the potential of cerebral white matter disorders to produce cognitive loss of sufficient severity to qualify as dementia. Neurologists have long understood that such a syndrome can
Christopher M. Filley
doaj +3 more sources
Episodic memory function is associated with multiple measures of white matter integrity in cognitive aging [PDF]
Frontiers in Human Neuroscience, 2012 Previous neuroimaging research indicates that white matter injury and integrity, measured respectively by white matter hyperintensities (WMH) and fractional anisotropy (FA) obtained from diffusion tensor imaging, differ with aging and cerebrovascular ...
Samuel Neal Lockhart +24 more
doaj +2 more sources
White Matter-Gray Matter Correlation Analysis Based on White Matter Functional Gradient
Brain SciencesBackground: The spontaneous fluctuations in functional magnetic resonance imaging (fMRI) signals of the brain’s gray matter (GM) have been interpreted as representations of neural activity variations.
Zhengjie Li +5 more
doaj +2 more sources
White matter changes underlie hypertension-related cognitive decline in older adults
NeuroImage: Clinical, 2023 Hypertension has been well recognized as a risk factor for cognitive impairment and dementia. Although the underlying mechanisms of hypertension-affected cognitive deterioration are not fully understood, white matter changes (WMCs) seem to play an ...
Zilin Li +4 more
doaj +1 more source
Regional vulnerability of brain white matter in vanishing white matter
Acta Neuropathologica Communications, 2023 Vanishing white matter (VWM) is a leukodystrophy that primarily manifests in young children. In this disease, the brain white matter is differentially affected in a predictable pattern with telencephalic brain areas being most severely affected, while ...
Jodie H.K. Man +7 more
doaj +1 more source
What's the Matter? White Matter? [PDF]
Neuron, 2000 Although many children acquire reading skills rapidly with some formal training, for others learning to read is among the most difficult challenges they face in the first few years at school. The reasons for these large individual differences in skill acquisition are still obscure, with the relative contribution of biological and environmental factors ...
Zeffiro, Thomas, Eden, Guinevere
openaire +2 more sources
Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction
Annals of Clinical and Translational Neurology, 2020 Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter degeneration ...
Nicole I. Wolf +15 more
doaj +1 more source
Interleukin-6, age, and corpus callosum integrity. [PDF]
, 2014 The contribution of inflammation to deleterious aging outcomes is increasingly recognized; however, little is known about the complex relationship between interleukin-6 (IL-6) and brain structure, or how this association might change with increasing age.
Bettcher, Brianne M +13 more
core +7 more sources
Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]
PLoS ONE, 2015 Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos +3 more
doaj +1 more source
White dwarfs and Galactic dark matter [PDF]
, 2002 We discuss the recent discovery by Oppenheimer et al (2001) of old, cool white dwarf stars, which may be the first direct detection of Galactic halo dark matter.
Flynn, Chris +2 more
core +3 more sources