Results 101 to 110 of about 289,950 (199)

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Validation of a Bead-Based Multiplex Assay for miRNA Quantification in Rat Liver Inflammation. [PDF]

ACS Omega
Lee EK, Jeon EJ, Han SH, Jang EY, Jung KJ.   +4 more
europepmc   +1 more source

Bladder cancer : selection of urinary biomarkers and development of a multiplex analytical tool for the diagnosis and recurrence of urothelial tumors

, 2016
Marine De Paoli
openalex   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Simple, fast, reliable: multiplex digital PCR quantification of 19 genetically modified soybean events. [PDF]

GM Crops Food
Jelenčič A, Štebih D, Demšar T, Dobnik D.   +3 more
europepmc   +1 more source

Engineering MnPt Bimetallic Nanozymes for Cascade Enzymatic Therapy and Enhanced Radio‐Immunotherapy

Advanced Science, EarlyView.
A CD44‐targeted MnPt bimetallic nanozyme (HD@MnO2) integrates multienzyme‐like activity with cGAS–STING activation to boost radio‐immunotherapy. Through cascade biocatalysis, it depletes glutathione, relieves hypoxia, and amplifies ROS, enhancing radiotherapy‐induced DNA damage and immunogenic cell death. The nanozyme promotes dendritic cell maturation
Wenyi Zhang, Yangyang Guo, Guoping Xu, Luhaoxiang Liu, Lin Chen, Cai Zhang, Yiming Li, Jianmin Li, Yang Zhao   +8 more
wiley   +1 more source

Diagnostic accuracy of ARK Checker® C/G-DyLight® 488: simultaneous detection of Giardia and Cryptosporidium by fluorescent antibody microscopy. [PDF]

Trop Med Health
Oshiro Y, Kawashima A, Akashi M, Yanagawa Y, Shimodaira K, Matsuzawa H, Nemoto T, Shimogawara R, Kurokawa M, Ando N, Uemura H, Aoki T, Yamamoto K, Akiyama J, Mizushima D, Kitazawa T, Gatanaga H, Yagita K, Watanabe K.   +18 more
europepmc   +1 more source

Analysis of individual HIV-1 budding event using fast AFM reveals a multiplexed role for VPS4

, 2022
Shimon Harel, Yarin Altaras, Dikla Nachmias, Noa Rotem‐Dai, Inbar Dvilansky, Natalie Elia, Itay Rousso   +6 more
openalex   +2 more sources

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Phage-based diagnostic assay for melioidosis using multiplex PCR targeting <i>Burkholderia</i> phage terminase genes. [PDF]

iScience
Withatanung P, Vanaporn M, Chantratita N, Chareonsudjai S, Muangsombut V, Janesomboon S, Asawalertsaeng T, Clokie MRJ, Galyov EE, Korbsrisate S.   +9 more
europepmc   +1 more source