Results 101 to 110 of about 654,517 (244)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Location Detection of False Data Injection Attacks in Power Grid Based on Improved Deep Extreme Learning Machine

发电技术
ObjectivesPower systems are facing threats of false data injection attacks. Existing detection methods for false data injection attacks have the problems of insufficient feature learning ability and slow detection speed, making it difficult to locate ...
XI Lei, WANG Yixiao, XIONG Yahui, DONG Lu   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Additive Injection and Flow Ratio Control Systems

Measurement + Control, 1977
J. J. Jiskoot
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Multi-period superstructure optimization for CCS source-sink matching in South Sumatra industrial clusters

Carbon Neutrality
Minimizing supply chain costs is a critical challenge for the successful deployment of full-chain CO₂ capture and storage (CCS) systems, particularly in industrial clusters with diverse source and sink characteristics.
Osaliana Budiarto, Widodo Wahyu Purwanto, Alin Halimatussadiah, Dara Ayuda Maharsi   +3 more
doaj   +1 more source

Research on Intelligent Diagnosis and Decision-Making Method for Oilfield Water Injection System Faults

IEEE Access
Water injection is a commonly used development method in oilfields. Water injection systems are large and complex, with horizontally and vertically interconnected pipeline networks often buried underground.
Ruijie Zhang, Wenting Yang, Jie Li, Shengliang Gao, Yan Wang, Sheng Gao   +5 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Digital Twin Modeling for Smart Injection Molding

Journal of Manufacturing and Materials Processing
In traditional injection molding, each level of the process has its own monitoring and improvement initiatives. But in the upcoming industrial revolution, it is important to establish connections and communication among all stages, as changes in one ...
Sara Nasiri, Mohammad Reza Khosravani, Tamara Reinicke, Jivka Ovtcharova   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source