Results 91 to 100 of about 1,209,776 (284)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

短时受精后早剥卵对胚胎质量及妊娠结局的影响

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2014
摘 要: 【目的】 探讨短时受精后早期剥除颗粒细胞对体外受精胚胎质量及妊娠结局的影响。【方法】 回顾性分析2012年在本中心助孕的有早剥卵的103个IVF周期与74个ICSI周期,以ICSI组为对照,比较两组的2PN受精率、多PN受精率、可利用胚胎形成率、卵裂期优质胚胎形成率、种植率和临床妊娠率,再以IVF周期中的卵子是否进行早剥分为两组,比较早剥对IVF周期中2PN受精率、多PN受精率、可利用胚胎形成率、卵裂期优质胚胎形成率、种植率和临床妊娠率的影响。【结果】在IVF周期中共有1181枚卵子纳入研究 ...
doaj  

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Polysomnography analysis of sleep in a cohort of children treated for brain tumour

open access: yes
Purpose: The knowledge of sleep disorders in children with brain tumours is limited. We aim to investigate the presence of possible sleep disturbances in this population. Methods: Polysomnography (PSG) analysis was performed in our Paediatric Clinic from
Michael  Vidoni   +6 more
core   +1 more source

小鼠心源性CD51阳性细胞的分离与鉴定

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2014
摘 要: 【目的】 探讨整合素蛋白αv(CD51)阳性细胞在小鼠正常心脏组织中的分布情况并鉴定其是否存在心肌干细胞相关特性。【方法】 通过免疫荧光染色,RT-PCR,Q-PCR等方法,观察CD51+细胞在C57小鼠心脏中的表达及分布情况;应用流式细胞仪进一步检测心脏中CD51的表达比例,并分选出CD51阳性细胞进行体外培养;利用CCK-8实验检测细胞增殖能力;细胞稳定传代后进行成骨、成脂诱导,检测其多向分化能力。【结果】实验结果显示小鼠心脏中存在CD51+细胞,随年龄增大其表达水平呈下降趋势;在出生7d
doaj  

North Korea’s Nuclear and Missile Programs

open access: yes, 2020
The international community has consistently underestimated North Korean nuclear and missile capabilities. How has an economically impoverished, technologically backward, and internationally isolated state been able to establish robust and increasingly competent nuclear weapons and ballistic missile programs?
Cheung, Tai Ming, Haggard, Stephan
openaire   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

子宫内膜癌患者代谢综合征及其组分发病情况

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2012
【目的】 探讨子宫内膜癌患者代谢综合征(MS)及其组分的发病情况,并与健康体检人群进行比较。【方法】 选取2005年9月至2009年12月在中山大学孙逸仙纪念医院妇科肿瘤专科进行初始治疗的子宫内膜癌患者265例为研究组,用年龄及绝经与否进行匹配的同期在我院体检中心进行体检的女性265例为对照组,对其临床资料进行回顾性分析。代谢综合征的诊断采用2005年国际糖尿病联盟制定的标准。【结果】 研究组MS发病率为41.89%,对照组MS的发病率为9.28%;研究组的腰围、BMI、收缩压、舒张压、TG ...
doaj  

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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