Results 131 to 140 of about 2,663,937 (342)

How Ethnic and Religious Nationalism Threaten the Bosnian State

open access: yes, 2020
When the wars ceased in the former Yugoslavia in the 1990s, as in the aftermath of other past conflicts in the Balkans, ethnic and religious divisions prevailed.
Hone, Matthew James
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Securitised Ethnic Identities and Communal Conflicts [PDF]

open access: yes, 1997
Excerpt The paper is inspired by Ernesto Laclau\u27s (1996, p. 46) observation of the terrain into which history has thrown us. The terrain is characterised by: [...] the multiplication of new--and not so new--identities as a result of the collapse of ...
Väyrynen, Tarja
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Dilemmas in providing humanitarian intervention in ethnic conflict: a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Development Studies [PDF]

open access: yes, 2004
This thesis explores the difficulties of providing humanitarian assistance in ethnic conflict situations, explaining the problems and offering suggestions to mitigate the consequences.
Haddon, Matthew Perry
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

How do Perceptions of Outgroups Indicate Barriers to Civil Society in Iraq? [PDF]

open access: yes, 2005
At the Iraq "liberation" in 2003, many of us asked, "Is there really hope for civil society to emerge from the chaos?" We guessed about how Sunni, Shi'a and Kurdish factions could be brought together, and if it was likely that ethnic conflicts would ...
Gresham, Dr. JN
core   +1 more source

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