Results 21 to 30 of about 12,390,722 (231)
Reseña del libro:"Seis antropólogos mexicanos", Alonso, María de la Soledad, María Baranda
Secuencia, 1985 +
Roberto García Moll
doaj +1 more source
VDAC1 is regulated by BRD4 and contributes to JQ1 resistance in breast cancer
Oncology Letters, 2019 Voltage-dependent anion channels (VDACs) are situated in the outer membrane of the mitochondria and serve as gatekeepers that control metabolite and ion exchange between the cytosol and mitochondria. VDAC1 is one of the most studied members of the VDAC protein family and is overexpressed in multiple types of cancer.
Yang, Guochao +7 more
openaire +3 more sources
Open Access Could Transform Drug Discovery: A Case Study of JQ1 [PDF]
Expert Opinion on Drug Discovery, 2016 The cost to develop a new drug from target discovery to market is a staggering $1.8 billion, largely due to the very high attrition rate of drug candidates and the lengthy transition times during development. Open access is an emerging model of open innovation that places no restriction on the use of information and has the potential to accelerate the ...
Arshad Z +9 more
openaire +3 more sources
Reseña del libro: La nueva ola del feminismo en México, Jaiven, Ana Lau
Secuencia, 1988 +
María Dolores París
doaj +1 more source
Report of Anaxipha exigua( Orth:Trigoidiidae) from iran [PDF]
نامه انجمن حشرهشناسی ایران, 2004 +
M. Mofidi-Neyestanak
doaj
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells
PLoS ONE, 2014 High level MYC expression is associated with almost all human cancers. JQ1, a chemical compound that inhibits MYC expression is therapeutically effective in preclinical animal models in midline carcinoma, and Burkitt's lymphoma (BL). Here we show that JQ1 does not inhibit MYC expression to a similar extent in all tumor cells. The BL cells showed a ∼90%
Fowler, Trent +8 more
openaire +6 more sources
NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy [PDF]
Molecular Cancer Therapeutics, 2015 Abstract Genetically engineered mouse models of lung cancer have demonstrated an important role in understanding the function of novel lung cancer oncogenes and tumor-suppressor genes identified in genomic studies of human lung cancer. Furthermore, these models are important platforms for preclinical therapeutic studies.
Chunxiao, Xu +9 more
openaire +2 more sources
Philippine Journal of PathologyObjective. This study aimed to determine the demographic profiles of admitted COVID-19 patients, the association of coagulation and platelet tests on COVID-19 severity and compare the coagulation and platelet profile across the spectrum of the disease ...
Ivana Ungajan-Galapon +2 more
doaj +1 more source