Reliability and Validity of the Japanese Version of the Exercise Self-Efficacy Scale in Older People Undergoing Lower Extremity Arthroplasty. [PDF]
Matsumura M+5 more
europepmc +1 more source
The Transmission of Sanqu Songs, Writers’ Reputation, and Literati Network in the Mid Ming: Local and Translocal Considerations [PDF]
Tan, Tian Yuan
core
Germline variants in CDKN2A wild‐type melanoma prone families
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen+5 more
wiley +1 more source
Beyond Efficacy: Ensuring Safety in Peptide Therapeutics through Immunogenicity Assessment. [PDF]
Achilleos K+3 more
europepmc +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Risk Management of Medication Errors: Improving the Quality of Pharmacotherapeutic Practice. [PDF]
Despott RA, Vella Bonanno P, Gauci C.
europepmc +1 more source
Regimi di accumulazione, democrazia e strutture di classe in Senegal [Accumulation regimes, Democracy and Class Structures in Senegal] [PDF]
Oya, Carlos
core
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
In Vitro Structure-Activity Relationship Stability Study of Antisense Oligonucleotide Therapeutics Using Biological Matrices and Nucleases. [PDF]
Lovrić J+7 more
europepmc +1 more source