Results 291 to 300 of about 278,683,873 (354)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Neurosurgical management for chronic and end-of-life pain in children: A systematic review. [PDF]

Pain Pract
Abdelmageed S, Villalba N, Bae G, Mossner JM, Adelhoefer SJ, Aravagiri K, Shah RD, Raskin JS.   +7 more
europepmc   +1 more source

Review of Michael Aung-Thwin, 'Mists of Ramanna: the legend that was lower Burma' [PDF]

, 2006
Charney, Michael W.
core  

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Muscle Strengthening Exercises for the Foot and Ankle: A Scoping Review Exploring Adherence to Best Practice for Optimizing Musculoskeletal Health. [PDF]

J Foot Ankle Res
Osborne JWA, Menz HB, Whittaker GA, Cotchett M, Landorf KB.   +4 more
europepmc   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Evaluating Problematic Smartphone Use Among Chinese Primary School Students Using SABAS: An IRT and Network Analysis. [PDF]

Int J Methods Psychiatr Res
Liu S, Chen Q, Li J, Zhu Y, Guo X, Zhao X.   +5 more
europepmc   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source

Genetic analysis of predicted vegetative biomass and biomass-related traits from digital phenotyping of strawberry. [PDF]

Plant Genome
Dalid C, Zheng C, Osorio L, Verma S, Abd-Elrahman A, Wang X, Whitaker VM.   +6 more
europepmc   +1 more source

Community-Powered Learning: A Qualitative Analysis of Postgraduate Medical Trainee Development Through Journal Club. [PDF]

Clin Teach
Murray AL, Walsh BH, Wiese A.
europepmc   +1 more source