Results 21 to 30 of about 3,838 (138)

Small Molecule Inhibitors of Protein-Protein Interactions [PDF]

open access: yes, 2014
Protein-protein interactions (PPIs) constitute a rising class of targets for the next generation of therapeutic intervention. Though they play a fundamental role in many biological processes and almost all pathological conditions including cancer ...
Khoury, Kareem
core  

The Versatility of Diazirines: Properties, Synthetic and Modern Applications

open access: yesChemistry – A European Journal, Volume 31, Issue 43, August 1, 2025.
Diazirines are 3‐membered heterocycles containing two nitrogen atoms connected by a double bond. They possess a multi‐faceted reactivity that holds great potential for organic synthesis. This review discusses their properties, modes of activation, and their many modern uses, underlining their underappreciated versatility: as carbene precursors, but ...
Mathieu L. Lepage, Emmanuel Gras
wiley   +1 more source

Light-emitting diodes and photodiodes in the deep ultra-violet range for absorption photometry in liquid chromatography, capillary electrophoresis and gas sensing [PDF]

open access: yes, 2016
Absorbance measurement in the deep ultra-violet range (below 300 nm) has been one of the most widely used detection methods for analytical techniques as a large number of organic compounds have strong absorption bands in the deep UV region.
Bui, Duy Anh
core   +1 more source

The Halogen Effect in [Cu(NHC)X] Compounds: A Case Study on the Anti‐Leishmania and Antiviral Activity of [Cu(IPr)X]

open access: yesChemistrySelect, Volume 10, Issue 31, August 15, 2025.
This study explores how changing halidesfrom Cl to Iinfluences ionic radius, antioxidant activity, and lipophilicity. These shifts significantly impact the biological potency of [Cu(IPr)X] compounds against Leishmania parasites and arboviruses. A strategic tweak in halogen identity paves the way for enhanced therapeutic performance in metal‐based drug ...
J. V. Fontes   +9 more
wiley   +1 more source

Study Of The Homogeneity Of Drug Loaded In Polymeric Films Using Near-infrared Chemical Imaging And Split-plot Design

open access: yes, 2015
Split-plot design (SPD) and near-infrared chemical imaging were used to study the homogeneity of the drug paracetamol loaded in films and prepared from mixtures of the biocompatible polymers hydroxypropyl methylcellulose, polyvinylpyrrolidone, and ...
Alexandrino G.L.   +3 more
core   +1 more source

Simulating evaporative wet and dry cycles in Gale crater, Mars using thermochemical modeling techniques

open access: yesMeteoritics &Planetary Science, Volume 60, Issue 8, Page 1704-1720, August 2025.
Abstract The aim of this work is to provide a model‐backed hypothesis for the formation of evaporites—sulfates, borates—in Gale crater using thermochemical modeling to determine constraints on their formation. We test the hypothesis that primary evaporites required multiple wet–dry cycles to form, akin to how evaporite assemblages form on Earth ...
D. Das   +12 more
wiley   +1 more source

The photochemical inheritance of Eduardo Lissi and Juan Grotewold and the intersystem crossings with other inheritances

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 4, Page 790-832, July/August 2025.
Eduardo Lissi, Dorita Adamo‐Lissi and Juan Grotewold in Aberystwyth, Wales, winter 1961. Upon their return to Buenos Aires in 1963, with their PhD degrees, Lissi and Grotewold started a Chemical Kinetics and Photochemistry group in the School of Sciences (University of Buenos Aires).
Silvia E. Braslavsky   +1 more
wiley   +1 more source

Chemical modification of enzymes and formulation for operational and storage stability

open access: yes, 2001
Doctorat en sciences (sciences chimiques) (CHIM 3)--UCL ...
Colacino, Franco
core  

Formação de micelas de cloreto de cetilpiridinio em soluções aquosas de dimetilsulfoxido, dimetilformamida e dimetilacetamida [PDF]

open access: yes, 1981
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciencias Fisicas e MatematicasA formação de micelas de cloreto de cetilpiridinio (CPC1) em soluções aquosas de dimetilsulfóxido (DMSO), dimetilformamida (DMF) e dimetilacetamida ...
Souza, Valmor Eretiano de
core  

Hypervalent adducts of chalcogen-containing peri-substituted naphthalenes; reactions of sulfur, selenium, and tellurium with dihalogens

open access: yes, 2010
The work in this project was supported by the Engineering and Physical Sciences Research Council (EPSRC)A range of structurally diverse compounds 1-15 {Nap[SPh]2•Br4 (Nap = naphthalene-1,8-diyl); Nap[SePh][EPh]•Br4 (E = Se, S); Nap[SePh]2•I2; Nap[SePh ...
Michael Bühl   +9 more
core   +1 more source

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