Results 91 to 100 of about 28,745,073 (219)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
What is positive special education?
This chapter highlights the theorical foundation of positive special education. The chapter begins with a summary of Seligman’s positive psychology and its precursor such as learned optimism. Then follows a definition of positive special education.
Reichenberg, Monica,
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2017 Alternativas de utilizacao; Composicao; Metodos de aplicacao (distribuicao); Resultados de pesquisa sobre a utilizacao de dejetos de suinos e bovinos na producao de graos, em plantio convencional e direto (Milho e soja); Beneficio/custo dos sistemas de ...
KONZEN, E. A.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Maturação fisiológica de milho doce e sua relação com a qualidade das sementes. [PDF]
, 2016 O conhecimento do ponto de maturidade fisiológica é de fundamental importância para orientação dos produtores na obtenção de sementes de alta qualidade.
OLIVEIRA, A. C. de +5 more
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Paths to positivity: exploring the dynamics of positive organizing [PDF]
This paper advances a theory about the way patterns of positive and negative organizing unfold. It is grounded in data collected from 58 individuals.
Rego, Arménio +2 more
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