Results 61 to 70 of about 28,745,073 (219)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Estratégias para incremento de digestibilidade de proteínas e sustentabilidade da produção de perus. [PDF]
RESUMO: O objetivo foi avaliar a eficácia da enzima protease em dietas de perus na digestibilidade. O estudo foi realizado na Embrapa Suínos e Aves e utilizou 144 perus machos (NICHOLAS SS) com um dia de idade, alojados em gaiolas metabólicas por 60 dias,
RIBEIRO, T. P. +6 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 1985 Includes bibliographical references (pages 351-359) and index.Print version record.The order structure of positive operators -- Components, homomorphisms and orthomorphisms -- Topological considerations -- Banach lattices -- Compactness properties of ...
Aliprantis, Charalambos D +3 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Evaluation of Positive Action Training Scheme (e-PATS)
, 2010 South West Yorkshire Partnership NHS Foundation Trust serves a population of approximately 1 million people living across the large geographical area of Calderdale, Kirklees and Wakefield.
Topping, Annie, Padgett, Kath
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Phenomenology of positive change : social growth
, 2014 This chapter exposes the theoretical background of Flow of Consciousness Theory, underlining the connections between Optimal Experience and the process of social change. The concept of cultural artifact is revised.
P. Inghilleri, Paolo Inghilleri
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source