In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Toposelective on-surface synthesis of curved π-extended oligomers based on bowl-shaped aromatics. [PDF]
Gómez-Gómez M +5 more
europepmc +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Impact of Counterions on the Electronic Structure and Optical Properties of Water-Soluble Au<sub>25</sub> Clusters. [PDF]
Verma M, Malola S, Häkkinen H.
europepmc +1 more source
Structural bioinformatic studies of eight integral transmembrane NADPH oxidases and their AlphaFold 3 predicted QTY analogs with reduced hydrophobicity. [PDF]
Hu T, Cheng R, Chen E, Zhang S.
europepmc +1 more source
The SQSTM1 L341V Variant Associated With Sporadic ALS Promotes the Accumulation of Enlarged Ubiquitin-Positive SQSTM1 Bodies. [PDF]
Shimakura K +5 more
europepmc +1 more source
DMS-informed secondary structure modeling of Epstein-Barr Virus LMP-1 pre-mRNA defines novel elements spanning introns. [PDF]
Eich TO +3 more
europepmc +1 more source
Adversarial Sequence Mutations in AlphaFold and ESMFold Reveal Nonphysical Structural Invariance, Confidence Failures, and Concerns for Protein Design. [PDF]
Feldman J, Brogi M, Skolnick J.
europepmc +1 more source
Structures and Deformation in Glaciers and Ice Sheets
Reviews of Geophysics, 2021Michael Hambrey, Stephen J A Jennings
exaly

