Results 81 to 90 of about 25,265,347 (168)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Maximal Regularity for Evolution Equations in Weighted L_p-Spaces
, 2003 Let X be a Banach space and let A be a closed linear operator on X. It is shown that the abstract Cauchy problem _ u(t) + Au(t) = f(t); t > 0; u(0) = 0; enjoys maximal regularity in weighted Lp-spaces with weights !(t) = t , where 1=p < , if and ...
Jan Prüss +3 more
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Oliver H. P. Scott Civil War letter
This collection contains a letter written by Maj. Oliver H. P. Scott, commanding the 3rd Iowa Cavalry at Helena, Ark., to Maj. John W.
Scott, Oliver H. P., 1815-1880
core
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Inequalities for the p-Angular Distance in Normed Linear Spaces
, 2007 New upper and lower bounds for the p-angular distance in normed linear spaces are given. Some of the obtained upper bounds are better than the corresponding results due to L. Maligranda recently established in the paper [Simple norm inequalities, Amer.
Dragomir, Sever S
core
H-Y-H-Y-H/fully_body_VSM: publication
<p><strong>Full Changelog</strong>: https://github.com/H-Y-H-Y-H/fully_body_VSM/commits/publication</p ...
ArthasL1, H-Y-H-Y-H, jiong lin
core +1 more source