Results 71 to 80 of about 14,899,830 (217)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2013 This is the post-print version of the Article. The official publised version can be accessed from the links below. Copyright @ 2013 Springer BaselEmploying the localized integral potentials associated with the Laplace operator, the Dirichlet, Neumann and
Mikhailov, SE +2 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
, 2011 This is the post-print version of the Article. The official published version can be found at the links below - Copyright @ 2011 Birkhäuser Boston.Some segregated systems of direct localized boundary-domain integral equations (LBDIEs) associated with ...
Mikhailov, SE +4 more
core +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Modelling granular soil to predict pressures on integral bridge abutments
Presented here is a granular soil model created to investigate the soil pressureswhich develop behind integral bridge abutments. The problem is introduced along with a briefsummary of the fundamental behaviour, the model produced, and the initial ...
Banks, J.R +3 more
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, 2010 This is the pre-print version of the article. The official published version can be obtained from the link below - Copyright @ 2011 Wiley-BlackwellSegregated direct boundary-domain integral equation (BDIE) systems associated with mixed, Dirichlet and ...
S.E. Mikhailov +5 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The Integral Trees with Spectral Radius 3
There are eleven integral trees with largest eigenvalue 3.Integral graphs;graph spectra ...
Brouwer, A.E., Haemers, W.H.
core