While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable [PDF]
In mammals, the three classical ras genes encode four highly homologous proteins, N-Ras, H-Ras, and the isoforms K-Ras 4A and 4B. Previous studies have shown that K-ras is essential for mouse development and that while K-ras 4A and 4B are expressed ...
Patek, C. E. +30 more
core +1 more source
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae. [PDF]
Potassium ion (K) channels have been observed in diverse viruses that infect eukaryotic marine and freshwater algae. However, experimental evidence for functional K channels among these alga-infecting viruses has thus far been restricted to members of ...
Kukovetz K. +36 more
core +1 more source
Clustering dichotomously scored items through functional k-means algorithm
In the educational field, it is common to analyze the probability of a correct response to a test item as a continuous function of the item parameters and the subject ability. This relation is given by the item response function.
Di Battista, Tonio; Dipartimento di Metodi Quantitativi e Teoria Economica, Università "G. d'Annunzio" Chieti-Pescara +1 more
core +1 more source
Dynamic BOLD functional connectivity in humans and its electrophysiological correlates [PDF]
Neural oscillations subserve many human perceptual and cognitive operations. Accordingly, brain functional connectivity is not static in time, but fluctuates dynamically following the synchronization and desynchronization of neural populations.
Verena Brodbeck +14 more
core +1 more source
Boosting BOLD fMRI by K-Space density weighted echo planar imaging [PDF]
Functional magnetic resonance imaging (fMRI) has become a powerful and influential method to non-invasively study neuronal brain activity. For this purpose, the blood oxygenation level-dependent (BOLD) effect is most widely used. T2* weighted echo planar
Andreas J Bartsch +14 more
core +2 more sources
Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+, K+-ATPase a3 missense mutant mice [PDF]
Missense mutations in ATP1A3 encoding Na+,K+-ATPase α3 have been identified as the primary cause of alternating hemiplegia of childhood (AHC), a motor disorder with onset typically before the age of 6 months. Affected children tend to be of short stature
Dawson, Neil +10 more
core +5 more sources
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Functional roles of Na,K-ATPase subunits
PURPOSE OF REVIEW: Na,K-ATPase is an oligomeric protein composed of alpha subunits, beta subunits and FXYD proteins. The catalytic alpha subunit hydrolyzes ATP and transports the cations.
Geering, K.
core +1 more source
Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier +18 more
wiley +1 more source
THE IMPLEMENTATION OF GRAMMATICAL FUNCTIONS IN FUNCTIONAL DISCOURSE GRAMMAR [PDF]
underlying representation in a more or less across the board fashion, only taking into consideration the language dependent semantic function hierarchy.
Bakker, D. +5 more
core

