Results 21 to 30 of about 7,921,324 (219)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

On Pseudo-K-spaces [PDF]

open access: yes, 2008
. In this note a class of topological spaces generalizing the k-spaces is introduced and investigated. Particular attention is given to the study of products of such spaces, in analogy to what is already known about k-spaces and quasi-k ...
Anna Maria Miranda   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

On spaces with point-countable $k$-systems [PDF]

open access: yes, 2004
summary:This paper deals with the behavior of $M$-spaces, countably bi-quasi-$k$-spaces and singly bi-quasi-$k$-spaces with point-countable $k$-systems.
Yoshioka, Iwao, Iwao Yoshioka
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Regular multilinear operators on C(K) spaces

open access: yes, 1999
The purpose of this paper is to characterise the class of regular continuous multilinear operators on a product of C(K) spaces, with values in an arbitrary Banach space.
Bombal Gordon, Fernando   +1 more
core   +1 more source

Rigidity for the spectral gap on rcd(K, ∞)-spaces

open access: yes, 2020
We consider a rigidity problem for the spectral gap of the Laplacian on an RCD(K, ∞)-space (a metric measure space satisfying the Riemannian curvature-dimension condition) for positive K.
Ketterer C.   +3 more
core   +1 more source

Hobson’s choice? Constraints on accessing spaces of creative production [PDF]

open access: yes, 2010
Successful creative production is often documented to occur in urban areas that are more likely to be diverse, a source of human capital and the site of dense interactions.
Champion, Katherine   +2 more
core   +1 more source

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