Results 31 to 40 of about 4,708,060 (239)

Sediment subduction in Hadean revealed by machine learning

Proceedings of the National Academy of Sciences of the United States of America
Significance The source of Earth’s oldest materials has been debated using traditional approaches to trace elements and isotopes of zircon. Using a single geochemical proxy, like P contents or oxygen isotopes, for source fingerprinting can be ambiguous ...
Jilian Jiang, Xinyu Zou, Ross N. Mitchell, Yigang Zhang, Yong Zhao, Q. Yin, Wei Yang, Xiqiang Zhou, Hao Wang, C. Spencer, Xiaocai Shan, Shitou Wu, Guangming Li, Kezhang Qin, Xianhua Li   +14 more
semanticscholar   +1 more source

Analysis of textile composite structures with finite Volume-p-Elements [PDF]

, 2007
Anisotropic textile composites show nonlinear deformation and complex fai- lure behaviour. In particular three-dimensional reinforced textile composites are characterised by an orthotropic material behaviour. To achieve the full po- tential of textile
Aschenbrenner, Lars, Hartung, Daniel, Teßmer, Jan   +2 more
core  

Virtually free pro-p groups whose torsion elements have finite centralizer

, 2007
A finitely generated virtually free pro-p group with finite centralizers of its torsion elements is the free pro-p product of finite p-groups and a free pro-p ...
Herfort, W., Zalesski, P. A.
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Effects of T- and P-odd weak nucleon interaction in nuclei: renormalizations due to residual strong interaction, matrix elements between compound states and their correlations with P-violating matrix elements

, 1994
Manifestations of P-,T-odd weak interaction between nucleons in nucleus are considered. Renormalization of this interaction due to residual strong interaction is studied.
A. Barroso, A. Bohr, A. Griffiths, A. Schafer, A.B. Migdal, C.M. Frankle, D. Boose, D. Cho, D.F. Zaretsky, D.F. Zaretsky, E. Blanke, E.M. Henley, F. Osterfeld, G. Adelberger, G. Bertsch, G.A. Lobov, G.E. Brown, I.B. Khriplovich, I.S. Towner, J. Speth, J.B. French, J.D. Bowman, J.F. Shriner, Jr., J.W. Negele, K. Goeke, L. Stodolsky, L.D. Landau, L.V. Inzhechik, L.V. Inzhechik, N. Auerbach, O. K. Vorov, O.P. Sushkov, O.P. Sushkov, O.P. Sushkov, P.A. Moldauer, P.K. Kabir, R. De Haro, S.G. Kadmensky, S.G. Kadmensky, S.K. Lamoreax, V. Klemt, V. V. Flambaum, V.A. Khodel, V.E. Bunakov, V.F. Dmitriev, V.M. Khatsymovsky, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, W.C. Haxton, Ya.B. Zeldovich   +55 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Elements of Environmental Decoherence [PDF]

, 1999
In this contribution I give a brief introduction to the essential concepts and mechanisms of decoherence by the environment. The emphasis will be not so much on technical details but rather on conceptual issues and the impact on the interpretation ...
Joos, Erich
core   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source