Results 41 to 50 of about 4,708,060 (239)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
The order of elements in Sylow $p$-subgroups of the symmetric group
, 2004 Define a random variable $\xi_n$ by choosing a conjugacy class $C$ of the Sylow $p$-subgroup of $S_{p^n}$ by random, and let $\xi_n$ be the logarithm of the order of an element in $C$.
Schlage-Puchta, Jan-Christoph
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Torus elements used in effective shock absorber [PDF]
, 1966 Energy absorbing device forces torus elements to revolve annularly between two concentric tubes when a load is applied to one tube. Interference forces can be varied by using torus elements of different thicknesses.
Cunningham, P., Platus, D. L.
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Inclusive J/psi and psi(2S) Production from B Decay in p p-bar Collisions
, 1999 Using information on B-meson fragmentation functions from CERN LEP 1 and adopting the nonrelativistic QCD factorization formalism proposed by Bodwin, Braaten, and Lepage, we predict the transverse-momentum distribution of J/psi mesons originating from ...
A. Ali +30 more
core +2 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
A Protocol for Generating Random Elements with their Probabilities
, 2014 We give an AM protocol that allows the verifier to sample elements x from a probability distribution P, which is held by the prover. If the prover is honest, the verifier outputs (x, P(x)) with probability close to P(x).
A. Bogdanov +7 more
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source