Results 91 to 100 of about 2,148,173 (240)
The Long-Term Direct and External Effects of Jewish Expulsions in Nazi Germany [PDF]
This paper provides causal evidence on long-term consequences of Jewish expulsions in Nazi Germany on the educational attainment and political outcomes of German children.
Akbulut-Yuksel, Mevlude, Yuksel, Mutlu
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Making Work Pay for the Elderly Unemployed: Evaluating Alternative Policy Reforms for Germany [PDF]
We evaluate three policy reforms targeted at older unemployed people: (i) an hourly wage subsidy, (ii) an in-work credit, and (iii) a subsidy of social security contributions on low wages.
Peter Haan, Viktor Steiner
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Impure Public Goods and Technological Interdependencies [PDF]
Impure public goods represent an important group of goods. Almost every public good exerts not only effects which are public to all but also effects which are private to the producer of this good.
Löschel, Andreas, Rübbelke, Dirk T. G.
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Eastern Germany in the fifth year - investment hammering in the basement? [PDF]
Rebuilding the capital stock will play the decisive role in the adjustment process in the eastern German economy. Investment increased from DM 92 billion in 1991 to 157 billion in 1994 (in current prices). It amounted to 60 percent of GDP. Investment has
Siebert, Horst
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Politicizing Social Inequality: Competing Narratives From the Alternative for Germany and Left-Wing Movement Stand Up. [PDF]
Front Sociol, 2020 Schmidtke O.
europepmc +1 more source
Rudolf Goldscheid (1870-1931) and the Economy of Human Beings [PDF]
The article begins firstly with a short biography of Rudolf Goldscheid both as a fiction writer and as a private scholar mainly in the field of sociology. Secondly, his most important scientific conception, the Economy of Human Beings, and especially its
Gudrun Exner
core +1 more source